Fatty acid composition of vegetable oil blend and in vitro effects of pharmacotherapeutical skin care applications

Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas
M GuidoniMarcio Fronza

Abstract

Vegetable oils have been used for a plethora of health benefits by their incorporation in foods, cosmetics, and pharmaceutical products, especially those intended for skin care. This study aimed to investigate the cutaneous benefits of a vegetable oil blend (VOB) formulation and its fatty acid composition. The anti-inflammatory activity was studied in macrophages of RAW 264.7 cells by investigating the release of nitric oxide (NO), superoxide anion generation (O2-), tumor necrosis factor-alpha (TNF-α), and interleukin 6 (IL-6). ABTS cation radical scavenging capacity assay, ferric reducing antioxidant potential (FRAP), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and NO free radical scavenging assays were used to evaluate the antioxidant activity. VOB was tested for its ability to stimulate fibroblast proliferation and migration using the scratch assay, and antibacterial activity by the microdilution test. The fatty acid profile of a freshly prepared VOB formulation was determined by gas chromatography before and after accelerated stability testing. Chemical composition of VOB revealed the presence of oleic acid (C18:1n-9; 63.3%), linoleic acid (C18:2n-6; 4.7%), and linolenic acid (C18:3n-6; 5.1%) as major mono- and polyunsaturated fa...Continue Reading

References

Oct 1, 1982·Analytical Biochemistry·L C GreenS R Tannenbaum
Jun 25, 1999·Free Radical Biology & Medicine·R ReC Rice-Evans
Aug 24, 2000·Journal of Agricultural and Food Chemistry·R PulidoF Saura-Calixto
Jul 10, 2003·Journal of Wound, Ostomy, and Continence Nursing : Official Publication of the Wound, Ostomy and Continence Nurses Society·Barbara Pieper, Maria Helena Larcher Caliri
Feb 3, 2006·Journal of Immunoassay & Immunochemistry·Hyung Sim ChoiChaekyun Kim
Oct 6, 2007·Cell Biochemistry and Function·Leonardo M PereiraTania C Pithon-Curi
May 13, 2008·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Jodi C McDanielWendy Blakely
May 16, 2008·Nature·Geoffrey C GurtnerMichael T Longaker
Jun 26, 2010·Journal of the American Academy of Dermatology·Stephan SchremlPhilipp Babilas
Apr 29, 2015·Pharmaceutical Biology·Cátia VittorazziMarcio Fronza
Mar 30, 2016·Nature Reviews. Drug Discovery·James N Fullerton, Derek W Gilroy
Jun 23, 2016·Journal of Ethnopharmacology·Luciane Souza Dos Santos GrammaMarcio Fronza
Sep 10, 2016·Military Medicine·Janice K Kiecolt-GlaserLisa M Christian
Jan 31, 2017·Planta medica·Franciane Martins MarquesMarcio Fronza
Feb 9, 2017·Pharmaceutical Biology·Jhéssica Benevides BahienseMarcio Fronza
Mar 10, 2017·Journal of Biomaterials Science. Polymer Edition·Supamas Napavichayanun, Pornanong Aramwit
Apr 20, 2017·International Journal of Dermatology·Rashmi SarkarVijay K Garg
May 17, 2017·Advanced Pharmaceutical Bulletin·Fataneh Hashempour-BaltorkGeoffrey Peter Savage
May 21, 2017·Lipids in Health and Disease·Aleksandra Zielińska, Izabela Nowak
Jun 28, 2017·BMC Complementary and Alternative Medicine·Berhan BegashawZewdneh Shewamene
Jul 15, 2017·American Journal of Clinical Dermatology·Alexandra R VaughnVivian Y Shi

❮ Previous
Next ❯

Citations

Jul 23, 2019·Phytotherapy Research : PTR·Adchara PrommabanSomdet Srichairatanakool
Oct 9, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·José Alex A SantosRafael M Ximenes

❮ Previous
Next ❯

Methods Mentioned

BETA
ELISA
enzyme-linked immunosorbent assay

Software Mentioned

CellC
GraphPad

Related Concepts

Related Feeds

Antiparasitics

Antiparasitics are medications which are indicated for the treatment of parasitic diseases. Discover the latest research on antiparasitics here.

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.

© 2022 Meta ULC. All rights reserved