Fatty acids profile and antiinflammatory activity of Nonea setosa R. et S

Phytotherapy Research : PTR
Massimo CuriniLuigi Menghini

Abstract

In order to verify the antiinflammatory properties of Nonea setosa R. et S. (Fam. Boraginaceae) and to identify the relevant active principles, aerial parts of this plant were extracted with increasing polarity solvents. The antiinflammatory activity was investigated by a bioassay-oriented fractionation using the inhibition of the croton oil-induced ear oedema in mice as an experimental model of inflammation. GC-MS analysis of the most active fraction revealed the presence of high amounts of polyunsaturated fatty acids.

References

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Jul 23, 2002·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Eckhard WollenweberJan F Stevens
Sep 24, 2004·Biomedical Chromatography : BMC·Tomasz MroczekKazimierz Glowniak
Mar 25, 2005·Biochemical Society Transactions·P C Calder

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