PMID: 6105125Mar 1, 1980Paper

Fatty liver and sudden death. A review

Human Pathology
B Randall

Abstract

Alcoholism is associated with increased mortality from violent and nonviolent causes. The increase in nonviolent deaths is usually ascribed, at least in part, to "cirrhosis." In the majority of these deaths this implies fatty liver rather than true Laennec's cirrhosis. Studies of sudden nonviolent deaths illustrate the largely unrecognized and frequent occurrence of sudden death with autopsy findings limited solely to fatty liver. The mechanism(s) of these sudden fatty liver deaths is unknown. Several attractive theories attribute such deaths to ethanol withdrawal induced hypoglycemia or hypomagnesemia, pulmonary fat embolization from fatty liver, or other facets of the alcohol withdrawal syndrome, including ethanol dependent maladaptive derangements of neurotransmitters. All the theories of fatty liver death remain essentially untested, however, owing to uncontrolled postmortem conditions and the lack of awareness of fatty liver deaths within the scientific community.

References

Apr 1, 1976·The New England Journal of Medicine·J Koch-WeserH Kalant
May 15, 1976·Biochemical Pharmacology·G Cohen
Jul 1, 1978·Clinics in Endocrinology and Metabolism·J Littleton
Jan 1, 1977·Advances in Experimental Medicine and Biology·H Kalant
Jul 1, 1978·The British Journal of Psychiatry : the Journal of Mental Science·J C Ballenger, R M Post
Jul 5, 1979·The New England Journal of Medicine·E Rubin
Jan 1, 1977·Advances in Experimental Medicine and Biology·H Begleiter, B Porjesz
Jul 1, 1978·Pharmacology, Biochemistry, and Behavior·J K BelknapR R Coleman
Jan 1, 1977·Advances in Experimental Medicine and Biology·E Majchrowicz
Apr 20, 1978·The New England Journal of Medicine·C S Lieber
Jan 1, 1976·Annals of the New York Academy of Sciences·S Cohen
May 1, 1975·Metabolism: Clinical and Experimental·J McMonagle, P Felig
Apr 30, 1973·Annals of the New York Academy of Sciences·D J Reis
Apr 30, 1973·Annals of the New York Academy of Sciences·F W Ellis, J R Pick
Apr 30, 1973·Annals of the New York Academy of Sciences·M J Wayner
Jan 1, 1968·Advances in Metabolic Disorders·L L Madison
Apr 30, 1973·Annals of the New York Academy of Sciences·M Victor
Apr 30, 1973·Annals of the New York Academy of Sciences·D B Goldstein
Apr 30, 1973·Annals of the New York Academy of Sciences·G Freund
Apr 30, 1973·Annals of the New York Academy of Sciences·M Victor
Jun 1, 1974·The British Journal of Addiction to Alcohol and Other Drugs·W Feuerlein
Apr 30, 1973·Annals of the New York Academy of Sciences·I GellerJ H Merritt
Feb 1, 1973·Annals of Internal Medicine·L J LevyE E Gordon
Feb 1, 1973·The Journal of Physiology·J S Haight, W R Keatinge
Mar 1, 1974·Preventive Medicine·L H KullerR Fisher
Jul 2, 1970·The New England Journal of Medicine·J H Mendelson
Mar 1, 1967·Epilepsia·M Victor, C Brausch
Nov 1, 1972·Metabolism: Clinical and Experimental·P Lim, E Jacob
Aug 15, 1969·Annals of the New York Academy of Sciences·J H MendelsonN K Mello
Aug 15, 1969·Annals of the New York Academy of Sciences·S M Wolfe, M Victor
Jul 1, 1969·American Journal of Public Health and the Nation's Health·L H KullerR Fisher
Jul 20, 1957·Lancet·M J LYNCHT P DIXON
Mar 1, 1958·Southern Medical Journal·J C HOLLERH R PRATT-THOMAS
Apr 1, 1961·American Heart Journal·W EVANS
Sep 1, 1961·Annals of Internal Medicine·M GOLDBERG, C M THOMPSON
Jun 8, 1962·Deutsche medizinische Wochenschrift·H THALER
May 24, 1963·Deutsche medizinische Wochenschrift·F BSCHOR
Sep 1, 1963·American Journal of Clinical Pathology·F E CUPPAGE
Mar 1, 1965·American Heart Journal·H A HEGGTVEIT
Oct 21, 1961·Lancet·P B NEAME, S M JOUBERT
Jul 1, 1962·The Journal of Surgical Research·G OWENS, M NORTHINGTON

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Citations

Dec 3, 1988·BMJ : British Medical Journal·A C ThomasM J Davies
Mar 4, 1999·Histopathology·M J Davies
Sep 1, 2011·The American Journal of Forensic Medicine and Pathology·D Kimberley Molina
Jan 1, 1984·The American Journal of Drug and Alcohol Abuse·N Beshai
May 1, 1981·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·H OrregoL M Blendis
Dec 18, 2013·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Cristian Palmiere, Marc Augsburger
Apr 1, 1983·Medicine, Science, and the Law·T T Tan
Jun 1, 1996·Journal of Clinical Pathology·A M Davison, S Leadbeatter
Jul 21, 2009·Forensic Science, Medicine, and Pathology·Neil E I Langlois
Jan 6, 2010·International Journal of Environmental Research and Public Health·Alexa H TempletonClare Verrill
Jan 1, 1997·The Journal of the American Dental Association·M Glick

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