PMID: 2500768Jan 1, 1989Paper

Fatty macroregenerative nodule in non-steatotic liver cirrhosis. A morphologic study

Virchows Archiv. A, Pathological Anatomy and Histopathology
T TeradaA Nonomura

Abstract

We here describe the morphologies of 9 macroregenerative nodules (MRNs) showing moderate to marked fatty change (fatty MRN) from 6 cases of non- or minimally-steatotic cirrhotic livers. In most of these cases, no obvious steatogenic factors of the liver were obtainable. These fatty MRNs showed more or less a sharp border. Seven of these fatty MRNs showed a variable degree of unusual morphological alterations suggestive of neoplasia: atypical and hyperchromatic nuclei, abnormal blood vessels, foci of clustering Mallory bodies, numerous hyaline globules, alpha-fetoprotein-positive hepatocytes, resistance to iron accumulation, infiltration into the portal tracts within MRN, and occurrence of hepatocellular carcinoma without fatty change. These observations suggest that at least some of the fatty MRNs are neoplastic or belong to a borderline lesion, and that the fatty change in the MRNs may be one of hepatocellular expressions related to human hepatocarcinogenesis.

References

Dec 1, 1972·Journal of the National Cancer Institute·W H Williams, R G Krueger
Jan 1, 1973·The Journal of Pathology·P P Anthony
Apr 1, 1981·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S M HsuH Fanger
May 6, 1980·Biochimica Et Biophysica Acta·G M Williams
Apr 1, 1951·The Journal of Pathology and Bacteriology·S YOUNG

❮ Previous
Next ❯

Citations

May 29, 1999·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M YamagataM Omata
Jan 1, 1993·Virchows Archiv. A, Pathological Anatomy and Histopathology·T TeradaY Nakanuma
Feb 11, 2005·Current Gastroenterology Reports·Morris Sherman
Sep 1, 1993·Baillière's Clinical Gastroenterology·D J Harrison, A D Burt
Jun 18, 1998·The American Journal of Surgical Pathology·Y N ParkN D Theise
Oct 1, 1995·Pathology International·Y Nakanuma
Mar 23, 2007·AJR. American Journal of Roentgenology·Jeong-Sik YuKi Whang Kim
Oct 1, 1994·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·K Jensen, C Gluud
Oct 1, 1992·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·N D TheiseS N Thung
May 24, 2008·International Journal of Surgical Pathology·Tadashi Terada, Makoto Sugiura
Jun 1, 1993·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·N D TheiseS N Thung
Mar 1, 1995·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·P HytiroglouS N Thung
Jun 30, 2000·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·L Ferrell
May 11, 2016·Hepatology Research : the Official Journal of the Japan Society of Hepatology·Tsutomu TamadaKatsuyoshi Ito
Jul 19, 2002·Clinics in Liver Disease·Neil D TheiseMasamichi Kojiro
Oct 12, 2010·Academic Radiology·Dong-Ho BangKwon-Ha Yoon

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Hepatocellular

Hepatocellular Carcinoma is a malignant cancer in liver epithelial cells. Discover the latest research on Hepatocellular Carcinoma here.

Adrenocortical Carcinoma

Hepatocellular carcinoma is the most common type of primary liver cancer and frequently occurs in individuals with chronic liver diseases like cirrhosis. Here is the latest research.

© 2022 Meta ULC. All rights reserved