Abstract
Rhythm control is indicated for patients suffering from symptomatic atrial fibrillation (AF), but remains difficult to establish. We investigated the long-term outcome of Cox maze III surgery in patients with symptomatic lone AF refractory to antiarrhythmic drug therapy. Patients with a history of symptomatic paroxysmal or persistent AF refractory for at least two class I or III antiarrhythmic drugs and without structural heart disease or bradyarrhythmias were included. All patients underwent Cox maze III surgery. Complete success was defined as the absence of AF without antiarrhythmic drugs beyond 3 months after the procedure, and partial success as the absence of AF with antiarrhythmic drug use. A total of 29 patients were included (27 male), with a mean age of 48 +/- 6 years. At the time of surgery, 11 patients (38%) had persistent AF. After a mean follow-up of 4.8 +/- 2.4 years, 79% of patients had complete success, and 2 patients (7%) were free of AF with antiarrhythmic drugs. At the end of follow-up, left ventricular fractional shortening was significantly improved (from 31% +/- 10% to 39% +/- 8%, p = 0.002), left atrial size was unchanged, exercise capacity was within normal ranges, and quality of life was comparable wit...Continue Reading
References
Aug 1, 1991·Stroke; a Journal of Cerebral Circulation·P A WolfW B Kannel
Mar 13, 1995·Archives of Internal Medicine·W M FeinbergR G Hart
Nov 15, 1993·The American Journal of Cardiology·L M RodriguezH J Wellens
Dec 9, 1996·Archives of Internal Medicine·I C Van GelderK I Lie
Mar 1, 1997·European Heart Journal·N YashimaK Hiramori
Aug 1, 1997·Journal of the American College of Cardiology·D W SohnY W Lee
Sep 3, 1998·The New England Journal of Medicine·M HaïssaguerreJ Clémenty
Nov 11, 1998·The American Journal of Cardiology·W B KannelD Levy
Mar 29, 2000·Circulation·M HaïssaguerreJ Clémenty
Apr 4, 2000·Circulation·E R JessurunJ M Ernst
Nov 22, 2000·Circulation·C PapponeS Chierchia
Nov 21, 2001·Circulation·C PapponeO Alfieri
Mar 6, 2002·Circulation·Hakan OralFred Morady
Jun 28, 2002·The New England Journal of Medicine·Joshua M CooperMichael V Orlov
Dec 6, 2002·The New England Journal of Medicine·D G WyseUNKNOWN Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) Investigators
Dec 6, 2002·The New England Journal of Medicine·Isabelle C Van GelderUNKNOWN Rate Control versus Electrical Cardioversion for Persistent Atrial Fibrillation Study Group
Jan 23, 2003·The Annals of Thoracic Surgery·Emile R JessurunWybren Jaarsma
Apr 12, 2003·Pacing and Clinical Electrophysiology : PACE·Rukshen WeerasooriyaMichel Haïssaguerre
Feb 5, 2004·The Annals of Thoracic Surgery·Hauw T SieAnand R Ramdat Misier
May 26, 2004·International Journal of Cardiology·Anton E TuinenburgHarry J G M Crijns
Oct 7, 2004·The Annals of Thoracic Surgery·Thomas J van BrakelJos G Maessen
Dec 18, 2004·Heart·J P BourkeS S Furniss
Jan 8, 2005·European Heart Journal·Thomas J van BrakelJos G Maessen
Feb 5, 2005·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Krishna KhargiThomas Deneke
Feb 23, 2005·Circulation·Riccardo CappatoAllan Skanes
Apr 27, 2005·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Kristina LemolaHakan Oral
Sep 13, 2005·The Journal of Thoracic and Cardiovascular Surgery·Jean NinetGerard L Champsaur
Citations
Nov 13, 2009·General Thoracic and Cardiovascular Surgery·Toshinori TotsugawaAtsuhisa Ishida
Apr 13, 2011·General Thoracic and Cardiovascular Surgery·Toshinori TotsugawaAtsuhisa Ishida
May 12, 2012·General Thoracic and Cardiovascular Surgery·Yoshimori ArakiYuichi Ueda
Oct 9, 2009·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Theo J KlinkenbergIsabelle C Van Gelder
Jun 13, 2012·Circulation·Michiel RienstraEmelia J Benjamin
Apr 2, 2013·The Annals of Thoracic Surgery·Anders AlbågeEva Berglin
May 31, 2011·The Annals of Thoracic Surgery·John M StulakHartzell V Schaff
Mar 1, 2011·The Annals of Thoracic Surgery·Kathleen L GradyPatrick M McCarthy
Nov 22, 2008·The Annals of Thoracic Surgery·Catharina LundbergGöran Kennebäck
Oct 24, 2007·The Annals of Thoracic Surgery·Tatjana FleckWilfried Wisser
Dec 15, 2015·The Annals of Thoracic Surgery·Anders AlbågeUNKNOWN Swedish Arrhythmia Surgery Group
Nov 19, 2013·Pacing and Clinical Electrophysiology : PACE·Birgitta I JohanssonEva Berglin
Jun 16, 2015·Journal of Cardiovascular Electrophysiology·Elsayed Abo-SalemKenneth M Nugent
Apr 28, 2007·The Annals of Thoracic Surgery·Ertan SagbasBurak Onan
Feb 15, 2008·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Eng S TanIsabelle C Van Gelder
May 10, 2016·Nature Reviews. Disease Primers·Gregory Y H LipDeirdre A Lane
Feb 11, 2011·São Paulo Medical Journal = Revista Paulista De Medicina·Shi-Min YuanLeonid Sternik