FDG-PET/CT imaging for staging and target volume delineation in conformal radiotherapy of anal carcinoma.

Radiation Oncology
Marco KrengliEugenio Inglese

Abstract

FDG-PET/CT imaging has an emerging role in staging and treatment planning of various tumor locations and a number of literature studies show that also the carcinoma of the anal canal may benefit from this diagnostic approach. We analyzed the potential impact of FDG-PET/CT in stage definition and target volume delineation of patients affected by carcinoma of the anal canal and candidates for curative radiotherapy. Twenty seven patients with biopsy proven anal carcinoma were enrolled. Pathology was squamous cell carcinoma in 20 cases, cloacogenic carcinoma in 3, adenocarcinoma in 2, and basal cell carcinoma in 2. Simulation was performed by PET/CT imaging with patient in treatment position. Gross Tumor Volume (GTV) and Clinical Target Volume (CTV) were drawn on CT and on PET/CT fused images. PET-GTV and PET-CTV were respectively compared to CT-GTV and CT-CTV by Wilcoxon rank test for paired data. PET/CT fused images led to change the stage in 5/27 cases (18.5%): 3 cases from N0 to N2 and 2 from M0 to M1 leading to change the treatment intent from curative to palliative in a case.Based on PET/CT imaging, GTV and CTV contours changed in 15/27 (55.6%) and in 10/27 cases (37.0%) respectively. PET-GTV and PET-CTV resulted significantl...Continue Reading

References

May 1, 1974·Diseases of the Colon and Rectum·N D NigroB Considine
Oct 2, 2001·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·R J MyersonB J Walz
Jun 7, 2005·International Journal of Radiation Oncology, Biology, Physics·Ilja Frank CiernikGabor Szekely
Jul 20, 2005·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Thomas G Trautmann, James H Zuger
Apr 22, 2006·International Journal of Radiation Oncology, Biology, Physics·Shane E CotterRobert J Myerson
Jan 24, 2007·Technology in Cancer Research & Treatment·Deep A PatelAlbert C Koong
Aug 21, 2007·International Journal of Radiation Oncology, Biology, Physics·Cynthia AndersonKaren Godette
Oct 13, 2007·International Journal of Radiation Oncology, Biology, Physics·Maria Chiara BassiMarco Krengli
Nov 13, 2007·International Journal of Radiation Oncology, Biology, Physics·Julie K SchwarzPerry W Grigsby
May 3, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Brandon T NguyenAndrew Scott
Jan 2, 2009·International Journal of Radiation Oncology, Biology, Physics·Robert J MyersonLisa A Kachnic
Jan 21, 2009·The British Journal of Radiology·B D P O'NeillG Brown
Apr 17, 2009·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Sabine Kathrin MaiDietmar Jörg Dinter

❮ Previous
Next ❯

Citations

Sep 27, 2012·Abdominal Imaging·Sachin S SabooNikhil Ramaiya
Feb 2, 2013·Current Oncology Reports·Ajay AggarwalRob Glynne-Jones
Sep 3, 2013·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·V VendrelyJ-P Maire
Feb 2, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·N J BhuvaM K Harrison
Sep 28, 2013·Abdominal Imaging·S Gourtsoyianni, V Goh
Jul 24, 2014·Future Oncology·Emma BownJustin M Yeung
Oct 24, 2014·AJR. American Journal of Roentgenology·Ankit AgarwalRathan M Subramaniam
Mar 24, 2012·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·R A BundschuhM Essler
Apr 24, 2013·International Journal of Radiation Oncology, Biology, Physics·Thomas ZilliAbdelkarim S Allal
Nov 3, 2012·Hematology/oncology Clinics of North America·Rob Glynne-Jones, Andrew Renehan
May 18, 2012·International Journal of Radiation Oncology, Biology, Physics·Massimiliano MistrangeloMario Morino
Jan 3, 2012·Clinical Radiology·I T Wells, B M Fox
May 17, 2011·International Journal of Radiation Oncology, Biology, Physics·Cécile OrtholanDidier Cowen
Dec 28, 2010·The Surgical Clinics of North America·Anthony Visioni, Julian Kim
Feb 5, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·R O PerezC A Buchpiguel
Sep 20, 2015·PET Clinics·Beant S GillSushil Beriwal
May 15, 2015·The Indian Journal of Radiology & Imaging·Archi Agrawal, Venkatesh Rangarajan
Mar 17, 2015·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·I TroussierJ Thariat
Dec 3, 2014·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Hanbing ShangWeiguo Zhao
Apr 28, 2016·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·Orla A Houlihan, Brian D P O'Neill
Aug 24, 2012·AJR. American Journal of Roentgenology·Rohit KochharMark Saunders
May 31, 2017·Acta Oncologica·Michel ZimmermannChristoph Oehler
Oct 4, 2017·The British Journal of Radiology·Aamer MahmudDerek Jonker
Jun 8, 2018·Diseases of the Colon and Rectum·David B StewartUNKNOWN Prepared on Behalf of the Clinical Practice Guidelines Committee of the American Society of Colon and Rectal Surgeons
Jan 26, 2011·Nature Reviews. Clinical Oncology·Johan BussinkWim J G Oyen
Jun 19, 2012·Diseases of the Colon and Rectum·Scott R SteeleUNKNOWN Standards Practice Task Force of the American Society of Colon and Rectal Surgeons
Jun 6, 2018·The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of Radiopharmaceutica·Philippe BulensKarin Haustermans
Jun 25, 2016·Nuclear Medicine Communications·Alexandra R TeagleSabina Dizdarevic
Feb 9, 2017·Clinical Physiology and Functional Imaging·Charlotte Birk ChristensenAnne K Berthelsen
May 27, 2020·Radiation Oncology·Daniel MartinEmmanouil Fokas
Apr 23, 2020·Radiation Oncology·M UnterrainerC Belka
Aug 1, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·N J BhuvaM K Harrison

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Methods Mentioned

BETA
biopsy
surgical resection

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