FDG-PET/CT in the evaluation of anal carcinoma

International Journal of Radiation Oncology, Biology, Physics
Shane E CotterRobert J Myerson

Abstract

Surgical staging and treatment of anal carcinoma has been replaced by noninvasive staging studies and combined modality therapy. In this study, we compare computed tomography (CT) and physical examination to [(18)F]-fluoro-2-deoxy-D-glucose-positron emission tomography/computed tomography (FDG-PET/CT) in the staging of carcinoma of the anal canal, with special emphasis on determination of spread to inguinal lymph nodes. Between July 2003 and July 2005, 41 consecutive patients with biopsy-proved anal carcinoma underwent a complete staging evaluation including physical examination, CT, and 2-FDG-PET/CT. Patients ranged in age from 30 to 89 years. Nine men were HIV-positive. Treatment was with standard Nigro regimen. [(18)F]-fluoro-2-deoxy-D-glucose-positron emission tomography/computed tomography (FDG-PET/CT) detected 91% of nonexcised primary tumors, whereas CT visualized 59%. FDG-PET/CT detected abnormal uptake in pelvic nodes of 5 patients with normal pelvic CT scans. FDG-PET/CT detected abnormal nodes in 20% of groins that were normal by CT, and in 23% without abnormality on physical examination. Furthermore, 17% of groins negative by both CT and physical examination showed abnormal uptake on FDG-PET/CT. HIV-positive patients...Continue Reading

References

Mar 11, 1976·American Journal of Surgery·G T Golden, J S Horsley
Jan 1, 1983·AJR. American Journal of Roentgenology·P M WeinermanA J Wein
Mar 15, 1984·Cancer·D B FrostR G Martin
Apr 30, 1995·International Journal of Radiation Oncology, Biology, Physics·P W GrigsbyC A Perez
Oct 2, 2001·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·R J MyersonB J Walz
Jul 10, 2003·International Journal of Clinical Oncology·Alistair J CochranToshiaki Saida
Sep 27, 2003·Lancet·Alexander M ScharkoC David Pauza
Mar 29, 2005·Diseases of the Colon and Rectum·Harunobu SatoDavid C C Bartolo
Jun 7, 2005·International Journal of Radiation Oncology, Biology, Physics·Wayne T LamoreauxBarry A Siegel
Jul 13, 2005·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Naveen SubhasRichard L Wahl
Jul 20, 2005·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Thomas G Trautmann, James H Zuger
Sep 15, 2005·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Charito LoveChristopher J Palestro

❮ Previous
Next ❯

Citations

Apr 17, 2009·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Sabine Kathrin MaiDietmar Jörg Dinter
Sep 27, 2012·Abdominal Imaging·Sachin S SabooNikhil Ramaiya
Nov 10, 2010·International Journal of Colorectal Disease·Laetitia VercellinoJean-Noël Talbot
Sep 16, 2011·International Journal of Clinical Oncology·Yusuke OkumaMasahiko Shibuya
Nov 22, 2007·Diseases of the Colon and Rectum·Phillip R FleshnerUNKNOWN Standards Practice Task Force, American Society of Colon and Rectal Surgeons
Apr 2, 2009·Current Oncology Reports·Brian G Czito, Christopher G Willett
Sep 3, 2013·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·V VendrelyJ-P Maire
Aug 27, 2013·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·N Charrier, I Brenot-Rossi
Sep 4, 2012·Clinics in Colon and Rectal Surgery·Shawn P Webb, Chong S Lee
Sep 4, 2012·Clinics in Colon and Rectal Surgery·Juan Lucas Poggio
Feb 23, 2007·Clinical Nuclear Medicine·Ba D NguyenMichael C Roarke
Jun 5, 2007·Current Opinion in Oncology·Prajnan DasJaffer A Ajani
Jan 15, 2010·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A H EngledowP B Boulos
Feb 2, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·G Branagan
Jul 26, 2011·AJR. American Journal of Roentgenology·Jessica M DavisonPatrick J Peller
Jan 30, 2014·Radiation Oncology·Daniela MusioVincenzo Tombolini
Oct 24, 2007·La Presse médicale·Jean-Noël TalbotJean-Didier Grange
Oct 24, 2014·AJR. American Journal of Roentgenology·Ankit AgarwalRathan M Subramaniam
Apr 30, 2013·Surgical Oncology Clinics of North America·Brian G Czito, Jeffrey Meyer
Nov 3, 2012·Hematology/oncology Clinics of North America·Rob Glynne-Jones, Andrew Renehan
May 18, 2012·International Journal of Radiation Oncology, Biology, Physics·Massimiliano MistrangeloMario Morino
Jan 3, 2012·Clinical Radiology·I T Wells, B M Fox
Oct 18, 2011·International Journal of Radiation Oncology, Biology, Physics·Joen SveistrupSvend Aage Engelholm
Aug 2, 2011·Clinical Lung Cancer·Deepthi ManiDavid M Aboulafia
May 17, 2011·International Journal of Radiation Oncology, Biology, Physics·Cécile OrtholanDidier Cowen
Apr 1, 2011·PET Clinics·Chiaojung Jillian Tsai, Prajnan Das
Nov 27, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·John H L MatthewsNigel A Spry
Aug 24, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Maarten Lambrecht, Karin Haustermans
Apr 27, 2010·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·M-V Moreau-Claeys, D Peiffert
Mar 17, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Elizabeth A KiddPerry W Grigsby
Jul 28, 2009·International Journal of Radiation Oncology, Biology, Physics·Massimiliano MistrangeloAntonio Mussa
May 27, 2009·Cancer radiothérapie : journal de la Société française de radiothérapie oncologique·M-V MoreauD Peiffert
Apr 28, 2009·Gastroentérologie Clinique Et Biologique·P W Grigsby
Mar 3, 2009·International Journal of Radiation Oncology, Biology, Physics·Robert J MyersonBenjamin R Tan
Mar 14, 2009·Clinical Oncology : a Journal of the Royal College of Radiologists·C CrowleyM D Leslie
Mar 7, 2009·Gastroentérologie Clinique Et Biologique·M Mistrangelo, M Morino
Mar 8, 2016·Practical Radiation Oncology·Kelly E GoldmanWinston W Lien
Nov 13, 2015·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Shanna A MatalonMichael H Rosenthal
May 3, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Brandon T NguyenAndrew Scott
Nov 13, 2007·International Journal of Radiation Oncology, Biology, Physics·Julie K SchwarzPerry W Grigsby
Aug 21, 2007·International Journal of Radiation Oncology, Biology, Physics·Cynthia AndersonKaren Godette
Jan 15, 2015·CA: a Cancer Journal for Clinicians·Ravi ShridharCharles R Thomas
Feb 24, 2009·International Journal of Radiation Oncology, Biology, Physics·Joseph C HodgesChristopher H Crane
Mar 15, 2015·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Mathieu GauthéUNKNOWN Fédération Francophone de Cancérologie Digestive (FFCD)
Apr 28, 2016·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·Orla A Houlihan, Brian D P O'Neill

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