Feasibility and accuracy of TRUS in the pre-treatment staging for rectal carcinoma in general practice

European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
H PtokI Gastinger

Abstract

Transrectal ultrasonography (TRUS) is the diagnostic tool of choice for local staging of rectal carcinoma. The accuracy in determining of tumour infiltration depth has been reported to reach 95% (on average, 85%). The aim of the study was to analyse the diagnostic accuracy of the TRUS in the clinical routine. From 01/01/2000 to 12/31/2003, all patients with rectal carcinoma were enrolled in a prospective multicenter observational study. In case of complete findings of pre-operative TRUS and post-operative histological investigation of the surgical specimen on the tumour infiltration depth, overall accuracy of TRUS was determined. Overall, 13,610 patients with rectal carcinoma were enrolled in the study. Five thousand and fifty-six subjects (37%) underwent TRUS. In 3,501 patients, TRUS finding (uT-stage) could be compared with the result of the definitive histologic investigation (pT-stage). The accuracy of TRUS in all T-stages was 65.8%. The highest sensitivity was achieved in the T3-stage (74.9%), while in T2, T1, and T4, it was 59.6, 59.0 and 31.1%, respectively. In discriminating tumour growth limited to the rectal wall vs that through the rectal wall into the neighboring tissue, TRUS-associated accuracy was 76.5%. There wer...Continue Reading

References

Aug 1, 1990·Diseases of the Colon and Rectum·W J OrromS M Goldberg
Mar 4, 2000·Diseases of the Colon and Rectum·B J Carmody, D P Otchy
Oct 19, 2000·World Journal of Surgery·T AkasuT Kakizoe
Apr 27, 2002·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·F MaruschH Lippert
Feb 21, 2003·The British Journal of Surgery·S G MackayM J Solomon
Apr 30, 2003·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·F MaruschUNKNOWN Studiengruppe "Kolon/Rektum Karzinome (Primärtumor)"
Jan 24, 2004·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·P HohenbergerCh Stroszczynski
Jul 21, 2004·The Surgical Clinics of North America·David M Schaffzin, W Douglas Wong
Nov 20, 2004·Radiology·Roy F A VliegenRegina G H Beets-Tan
Apr 27, 2005·Clinical Radiology·A TaylorS Halligan

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Citations

Jun 16, 2011·Abdominal Imaging·Monique MaasRegina G H Beets-Tan
Sep 11, 2013·Journal of Visceral Surgery·C LartigauA Alves
Dec 17, 2009·Clinics in Colon and Rectal Surgery·John Touzios, Kirk A Ludwig
Aug 1, 2007·Clinics in Colon and Rectal Surgery·James S Wu
Aug 1, 2008·Clinics in Colon and Rectal Surgery·Bret R Edelman, Martin R Weiser
Sep 17, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·S AshrafUNKNOWN Association of Coloproctology of Great Britain and Ireland Transanal Endoscopic Microsurgery (TEM) Collaboration
May 11, 2012·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·H PtokH Lippert
Oct 5, 2010·Surgical Oncology Clinics of North America·Geerard L Beets, Regina G H Beets-Tan
Jul 15, 2009·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Vincenzo ValentiniUNKNOWN Scientific Committee
Apr 22, 2011·Journal of Magnetic Resonance Imaging : JMRI·Regina G H Beets-Tan, Geerard L Beets
Nov 5, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Cornelis J H van de VeldeVincenzo Valentini
Jan 23, 2015·Surgical Endoscopy·Mario MorinoUNKNOWN European Society of Coloproctology
Nov 25, 2016·Acta chirurgica Belgica·Bart Op de BeeckUNKNOWN PROCARE
Jan 31, 2009·Acta Oncologica·Gunnar BaatrupArild Nesbakken
Sep 17, 2010·Acta Oncologica·Vincenzo Valentini, Bengt Glimelius
Jul 19, 2018·Minerva chirurgica·Rebecca K RowenJohn R Monson
Jul 21, 2009·Diseases of the Colon and Rectum·Marc Beer-GabelBinjamin Avidan
Mar 28, 2008·Scandinavian Journal of Gastroenterology·Søren R RafaelsenJan Lindebjerg
Mar 13, 2018·Innovative Surgical Sciences·Dietmar TamandlAhmed Ba-Ssalamah
Apr 9, 2019·Biomedical Engineering Letters·Jeong Seok KimJae Young Lee
Sep 1, 2013·EJC Supplements : EJC : Official Journal of EORTC, European Organization for Research and Treatment of Cancer ... [et Al.]·Doenja M J Lambregts, Regina G H Beets-Tan

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