Feasibility and construct validity of a Frailty index for patients with chronic kidney disease

Australasian Journal on Ageing
Ruth E HubbardDavid W Johnson

Abstract

To determine whether the frailty status of patients with chronic kidney disease (CKD) can be measured using a Frailty index (FI). One hundred and eleven attending a nephrology clinic were approached to complete a one-page questionnaire evaluating cognitive, psychological and functional status. Data were coded as deficits, summed and divided by the total number of deficits considered, to derive an FI-CKD. One hundred and ten (mean age 65.2 years) agreed to participate and assessments took approximately 10 minutes to complete. Mean FI-CKD was 0.25 (SD 0.12). The FI-CKD increased with age at 3% per year, correlated with a modified Fried phenotype (P < 0.001) and increased significantly across CKD stages (P = 0.04). The FI-CKD is feasible in the outpatient setting and has good construct validity. The greater granularity of a continuous measure has the potential to inform decision-making regarding appropriate interventions for patients at the 'frail' end of the health spectrum.

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Citations

Jul 13, 2016·The Canadian Journal of Cardiology·Kenneth Rockwood
Nov 5, 2016·Archives of Gerontology and Geriatrics·Rakin ChowdhuryRuth E Hubbard
Apr 20, 2017·Journal of the American Geriatrics Society·Jeremy WalstonArti Hurria
Sep 16, 2018·International Journal of Colorectal Disease·Simon J G RichardsMark B Hampton
Sep 16, 2018·BMC Cancer·A L McCarthyR E Hubbard
Apr 17, 2019·The Journal of Rheumatology·Alexandra LeggeJohn G Hanly
Apr 13, 2018·Clinical Kidney Journal·Andrew C NixonAjay Dhaygude
Oct 30, 2018·Journal of the American Heart Association·Ashish PatelAkshay Bagai
May 4, 2017·BMC Nephrology·David A ClarkKarthik K Tennankore
Jul 7, 2020·The Journal of Clinical Endocrinology and Metabolism·Sumitabh SinghIrina Bancos
Mar 4, 2017·Biogerontology·A B MitnitskiK Rockwood
Feb 2, 2021·The Journal of Vascular Access·Kulli Kuningas, Nicholas Inston
Jun 3, 2021·International Journal of Environmental Research and Public Health·Anna TornéJordi Amblàs-Novellas
Jun 12, 2021·Transplantation Direct·Rhea A VarugheseLianne G Singer

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