Feasibility and early experience of a novel multidisciplinary alcohol-associated liver disease clinic.

Journal of Substance Abuse Treatment
Jessica L MellingerAnna S F Lok

Abstract

Alcohol cessation improves mortality in alcohol-associated liver disease (ALD), but access to treatment is limited. To address this gap, implementation and early feasibility and outcomes of a multidisciplinary ALD clinic are described. The clinic comprised a hepatologist, psychiatrist, psychologist, nurse, and social worker. Patients included those with alcohol-associated cirrhosis or acute alcoholic hepatitis who were not in the transplant evaluation process, who had less than 6 months' sobriety and willingness to engage in alcohol use treatment. Psychosocial metrics in addition to routine hepatic function labs were collected. Treatment plans were tailored based on patient preferences and needs after multidisciplinary discussion. 89 patients were referred from both inpatient and outpatient settings, with 51 seen during the initial year. 38 remained active in clinic (4 died, 6 discharged, 3 moved to transplant clinic). 55% were women, 88% were white, 61% had private insurance. 49% had alcoholic hepatitis. 71% were decompensated. 80% had severe alcohol use disorder (AUD) and 84% had at least 1 comorbid psychiatric or substance use disorder. 63% chose one-on-one AUD treatment, 57% were prescribed relapse prevention medications. M...Continue Reading

References

Jan 1, 1982·Addictive Behaviors·H A Skinner
May 24, 2006·Archives of Internal Medicine·Robert L SpitzerBernd Löwe
Aug 11, 2015·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Anam KhanFasiha Kanwal
Oct 6, 2017·Alcoholism, Clinical and Experimental Research·Megan ComerfordDavid W Crabb
Mar 27, 2018·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Jessica L MellingerAnna S F Lok
Jul 20, 2018·BMJ : British Medical Journal·Elliot B Tapper, Neehar D Parikh
Dec 27, 2018·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Fasiha KanwalMichael Volk
Jan 12, 2019·Journal of General Internal Medicine·Sarah E WakemanJoshua P Metlay
Jan 23, 2019·Alcoholism, Clinical and Experimental Research·Jessica L MellingerAnna S F Lok
Jun 27, 2019·Clinical Liver Disease·Jessica L Mellinger
Jul 18, 2019·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·David W CrabbMichael R Lucey

❮ Previous
Next ❯

Citations

Nov 3, 2021·Nature Reviews. Gastroenterology & Hepatology·Juan Pablo ArabVijay H Shah

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

JAMA : the Journal of the American Medical Association
Ashwani K Singal, Philippe Mathurin
Current Opinion in Gastroenterology
Margarita N GermanMichael R Lucey
Gastroenterology & Hepatology
Faisal A SiddiqiNyan L Latt
Clinics in Liver Disease
Sen HanSuthat Liangpunsakul
Hepatology : Official Journal of the American Association for the Study of Liver Diseases
Sumeet K AsraniVijay H Shah
© 2021 Meta ULC. All rights reserved