Abstract
Living-donor liver transplantation (LDLT) has been widely performed in patients with end-stage liver disease and hepatocellular carcinoma in Japan. Although extrahepatic cancer survey for LDLT candidates is absolutely required, few reports have indicated the optimal surveillance method for colorectal cancer. The aim of this study is to investigate the feasibility and findings of colonoscopy before LDLT. From January 2004 to August 2006, we prospectively enrolled all of the scheduled LDLT candidates of our hospital for pretransplant colonoscopy examination. A total of 81 patients were enrolled for colonoscopy. Of these patients, 67 (83%) could actually undergo colonoscopy. Patients who could not undergo colonoscopy exhibited more impaired liver function than those who could (median Model End-Stage Liver Disease score; 25.5 vs. 14.5, P=0.0003). Among patients who underwent colonoscopy, observation of total colon was attained in 64 (96%). Neoplasia was found in 28 (42%) patients, including 4 patients with adenomas > or =10 mm, 1 patient with adenomas with high-grade dysplasia, and 3 patients with invasive cancer. Patients who had advanced neoplasia (adenoma > or =10 mm, adenomas with high-grade dysplasia, or invasive cancer) were ...Continue Reading
References
Apr 1, 1992·Gut·S NaveauA Aubert
Jul 1, 1990·Gastroenterology·M RabinovitzJ S Gavaler
Dec 1, 1982·American Journal of Clinical Oncology·M M OkenP P Carbone
Mar 14, 1996·The New England Journal of Medicine·V MazzaferroL Gennari
Jul 1, 1996·Gastrointestinal Endoscopy·S KudoH Watanabe
Aug 1, 1997·Transplantation Proceedings·J A SelingoR A Rubin
Aug 26, 1998·The American Journal of Gastroenterology·D A WellerJ L Riegler
Apr 14, 1999·The American Journal of Gastroenterology·A ZamanK Benner
Feb 24, 2001·Journal of Hepatology·E B HaagsmaP L Jansen
Jun 21, 2001·Digestive Diseases and Sciences·S Y TungM Y Su
Mar 23, 2002·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Edmund Q SanchezGoran B Klintmalm
Aug 21, 2004·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A ZaniboniUNKNOWN Gruppo Italiano per lo Studio e la Cura dei Tumori del Digerente
Dec 4, 2004·Endoscopy·K-I FuT Fujimori
Apr 22, 2005·Endoscopy·S P MisraJ S Arora
Aug 9, 2005·Gastroenterology·Tamiya MorikawaYasushi Shiratori
Aug 30, 2005·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·O Visser, F E van Leeuwen
Oct 8, 2005·Transplantation·Ye H OoJames M Neuberger
Oct 28, 2005·Transplantation·Joseph F BuellE Steve Woodle
Mar 23, 2006·World Journal of Gastroenterology : WJG·Shigeharu KatoTakahiro Fujimori
May 10, 2006·Gut·T UraokaT Fujii
Sep 27, 2006·Endoscopy·G BresciA Capria
Sep 29, 2006·Gut·Han-Mo ChiuHsiu-Po Wang
Nov 3, 2006·The New England Journal of Medicine·Jaroslaw RegulaEugeniusz Butruk
Apr 18, 2007·Experimental Dermatology·Maren WeischerMark Berneburg
May 25, 2007·Drugs·Alex Gutierrez-Dalmau, Josep M Campistol
Citations
Jun 11, 2009·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·J B AlbrightJ Aranda-Michel
Feb 16, 2019·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Rosalie C OeyRobert A de Man
Jul 9, 2014·Diseases of the Colon and Rectum·Ho-Su LeeJeong-Sik Byeon
Jun 19, 2019·United European Gastroenterology Journal·Amelie S TroschelIyad Kabar
Feb 9, 2017·BioMed Research International·Kawano SeijiOkada Hiroyuki