Feasibility and Robustness of 3T Magnetic Resonance Angiography Using Modified Dixon Fat Suppression in Patients With Known or Suspected Peripheral Artery Disease

Frontiers in Cardiovascular Medicine
Karl Jakob WeissSebastian Kelle

Abstract

Objective: Contrast-enhanced magnetic resonance angiography (CE-MRA) is a well-established non-invasive imaging technique for the assessment of peripheral artery disease (PAD). A subtractionless method using modified Dixon (mDixon) fat suppression showed superior image quality at 1.5T over the common subtraction method, using a three-positions stepping table approach with a single dose of contrast agent. The aim of this study was to investigate the feasibility of subtractionless first-pass peripheral MRA at 3T in patients with known or suspected PAD and to compare the performance in terms of vessel-to-background contrast (VBC), signal-to-noise ratio (SNR), and subjective image quality to conventional subtraction MRA. Methods: Ten patients [mean age 69 years ± 12 standard deviation (SD)] with known or suspected PAD were examined on a clinical 3T scanner (Ingenia, Philips Healthcare, Best, Netherlands) at three table positions using subtractionless and subtraction first-pass peripheral MRA. Two readers rated image quality on a four- point scale. Interobserver agreement was expressed in quadratic weighted κ values. VBC was assessed with a semi-automated process and SNR was compared in a healthy volunteer. Results: Subjective image...Continue Reading

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Methods Mentioned

BETA
imaging technique

Software Mentioned

SPSS
mDixon

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