Feasibility and safety of endoscopic submucosal dissection for large colorectal tumors

Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
Shinwa TanakaTakeshi Azuma

Abstract

Recently, endoscopic submucosal dissection (ESD) has been applied for superficial colorectal neoplasms and the number of publications about it has been increasing, but little is known about the outcomes of colorectal ESD for the lesions > 50 mm. In this study, we evaluated the feasibility and safety of colorectal ESD for the lesions > 50 mm compared with the lesions < 50 mm. A total of 674 superficial colorectal neoplasms in 629 patients treated by ESD at Kobe University Hospital from July 2008 to July 2013 were included in the analysis. The median operation time (range) in the large lesion group (≥ 5 cm) was 109 (37 to 596) minutes, and it was 55 (6 to 248) minutes in the small lesion group (< 5 cm). Median procedure speed (range) in the large lesion group was 0.28 (0.06 to 0.83) cm2/min, and it was 0.19 (0.04 to 0.83) cm2/min in the small lesion group. The en bloc resection rate and the curative resection rate in the small lesion group was 98.7% and 96.0%, and those were 95.7% and 91.4% in the large lesion group, respectively. In terms of adverse events, perforation, muscle damage, and postoperative bleeding occurred at similar frequency in both groups. ESD on colorectal lesions > 50 mm takes longer operation time; however, i...Continue Reading

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Citations

Jun 28, 2016·Best Practice & Research. Clinical Gastroenterology·Matthew E Feurer, Peter V Draganov
Jul 29, 2016·World Journal of Gastroenterology : WJG·Shinwa TanakaTakeshi Azuma
Jun 30, 2016·Nature Reviews. Gastroenterology & Hepatology·Brian P Saunders, Zacharias P Tsiamoulos
Jul 30, 2021·Scandinavian Journal of Gastroenterology·Kazuya MiyaguchiShomei Ryozawa

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Methods Mentioned

BETA
dissection
sedation

Software Mentioned

SPSS Statistics

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