Abstract
To examine the feasibility and safety of performing cesarean myomectomy on pregnant women with myomas compared to cesarean section only. We retrieved English articles in the PubMed, Cochrane Library, Medline and EMBASE databases from inception to April 2020. Observational studies including the comparison of patients who underwent cesarean myomectomy and cesarean section, as well as those reporting perioperative outcomes were selected. Data extraction was conducted using RevMan 5.3. Twenty-three studies comprising 8,016 women were included in the meta-analysis. Of these, 3,955 underwent cesarean myomectomy, while 4,061 underwent cesarean section only. Cesarean myomectomies were associated with a greater decline in mean hemoglobin (mean difference [MD] 0.20 g/dL, 95% confidence intervals [CI] 0.06, 0.35, p = .007), greater incidence of hemorrhage (odds ratio [OR] 1.46, 95% CI 1.06, 2.01, p = .02), greater volume of blood loss (MD 45.54 ml, 95% CI 2.68, 88.41, p = .04), higher transfusion rate (OR 1.47 95%CI 1.09, 1.99, p = .01), longer operation duration (MD 10.40 min, 95% CI 8.54, 12.25, p < .001), or longer postoperative hospitalization (MD 0.18 d, 95% CI 0.12, 0.24, p < .001), compared to those who underwent cesarean section o...Continue Reading
References
Jan 1, 1994·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·D LoisE Paraskevaidis
Jan 31, 2002·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·E Y Kwawukume
Sep 6, 2003·ANZ Journal of Surgery·Karem SlimJacques Chipponi
Jul 20, 2004·BMC Pregnancy and Childbirth·Ashley S Roman, Khalil MA Tabsh
Oct 30, 2004·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·D BrownM Reid
Jan 27, 2005·Obstetrical & Gynecological Survey·Natalie Paloma Cooper, Stanley Okolo
Apr 26, 2005·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·O KaymakL Mollamahmutoglu
Feb 20, 2007·Annals of the New York Academy of Sciences·D HassiakosK Papadias
Dec 19, 2008·Acta Obstetricia Et Gynecologica Scandinavica·Hui LiMingying Liu
Jul 28, 2009·Journal of Clinical Epidemiology·Alessandro LiberatiDavid Moher
Oct 24, 2009·Fertility and Sterility·Babasaheb R DesaiJayashree C Ruge
Feb 13, 2010·The Journal of Obstetrics and Gynaecology Research·Byung-Joon Park, Yong-Wook Kim
May 25, 2010·The Journal of Obstetrics and Gynaecology Research·Jui-Yu LinWei-Min Liu
Jul 6, 2010·The Journal of Obstetrics and Gynaecology Research·Yun-Sook KimDong-Han Bae
Nov 16, 2010·Archives of Gynecology and Obstetrics·Jeong-Heon Lee, Dong-Hyu Cho
Mar 20, 2013·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Dianrong SongJie Guo
May 15, 2013·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Andrea TinelliMichael Stark
Jan 1, 2014·BJOG : an International Journal of Obstetrics and Gynaecology·Eric Jauniaux, Khalid S Khan
Sep 30, 2014·Obstetrics & Gynecology Science·Dam Hye KwonKeun Young Lee
Mar 18, 2015·Ginekologia polska·Radmila SparićAndrea Tinelli
May 30, 2015·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Hasan O TopçuNuri Danışman
Jun 17, 2016·Ginekologia polska·Aykut ÖzcanMehmet Ozeren
Jun 23, 2016·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Radmila SparićAndrea Tinelli
Aug 24, 2016·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Mehmet Ozgur AkkurtMekin Sezik
Aug 26, 2016·Archives of Gynecology and Obstetrics·I DedesC Haslinger
Dec 8, 2016·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Murat AkbasGokhan Demirayak
Jan 25, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Şafak HatırnazGokhan S Kılıç
Feb 9, 2017·The Journal of Obstetrics and Gynaecology Research·Radmila SparićAndrea Tinelli
Jun 7, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Radmila SparićAndrea Tinelli
Jun 25, 2017·BJOG : an International Journal of Obstetrics and Gynaecology·S Y HuangP J Cheng
Nov 8, 2017·Obstetrics and Gynecology·Vasilios PergialiotisStergios K Doumouchtsis
Dec 5, 2017·Geburtshilfe und Frauenheilkunde·Mehmet Baki SenturkAhter Tanay Tayyar
Mar 2, 2018·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Kiguna SeiKenichi Furuya
Nov 13, 2018·Journal of Obstetrics and Gynaecology of India·Anahita R Chauhan
Feb 1, 2019·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Radmila SparićAndrea Tinelli
Jun 18, 2019·BioMed Research International·Yinghao Yu, Jijun Zhao
Feb 18, 2020·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Şafak HatırnazAndrea Tinelli
Apr 8, 2020·Journal of Obstetrics and Gynaecology of India·Askın Evren GulerMuhittin Tamer Mungan