Feasibility of a multigroup deterministic solution method for three-dimensional radiotherapy dose calculations.

International Journal of Radiation Oncology, Biology, Physics
Oleg N VassilievFiras Mourtada

Abstract

To investigate the potential of a novel deterministic solver, Attila, for external photon beam radiotherapy dose calculations. Two hypothetical cases for prostate and head-and-neck cancer photon beam treatment plans were calculated using Attila and EGSnrc Monte Carlo simulations. Open beams were modeled as isotropic photon point sources collimated to specified field sizes. The sources had a realistic energy spectrum calculated by Monte Carlo for a Varian Clinac 2100 operated in a 6-MV photon mode. The Attila computational grids consisted of 106,000 elements, or 424,000 spatial degrees of freedom, for the prostate case, and 123,000 tetrahedral elements, or 492,000 spatial degrees of freedom, for the head-and-neck cases. For both cases, results demonstrate excellent agreement between Attila and EGSnrc in all areas, including the build-up regions, near heterogeneities, and at the beam penumbra. Dose agreement for 99% of the voxels was within the 3% (relative point-wise difference) or 3-mm distance-to-agreement criterion. Localized differences between the Attila and EGSnrc results were observed at bone and soft-tissue interfaces and are attributable to the effect of voxel material homogenization in calculating dose-to-medium in EGS...Continue Reading

References

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Apr 21, 2006·Physics in Medicine and Biology·Kent A GiffordFiras Mourtada

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Citations

Jul 21, 2011·Radiation Oncology·Antonella FogliataLuca Cozzi
Jul 21, 2009·Medical Physics·Mark J RivardLuc Beaulieu
Jul 23, 2011·Medical Physics·P TsiamasP Zygmanski
Mar 24, 2016·Australasian Physical & Engineering Sciences in Medicine·Jackson M ZifodyaWen-Long Hsieh
Mar 17, 2017·Journal of Applied Clinical Medical Physics·Liyong LinChristopher Ainsley
Aug 24, 2017·Journal of Applied Clinical Medical Physics·Chenyu YanM Saiful Huq
Jan 9, 2010·Physics in Medicine and Biology·Oleg N VassilievFiras Mourtada
Sep 22, 2016·Journal of Medical Physics·Gangarapu Sri KrishnaPalreddy Yadagiri Reddy
Feb 18, 2010·Journal of Applied Clinical Medical Physics·Kent A GiffordFiras Mourtada
Jan 14, 2021·Biomedical Physics & Engineering Express·Baljeet SeniwalTelma C F Fonseca
Jun 5, 2020·Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznań and Polish Society of Radiation Oncology·Lalit KumarMunish Gairola

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