Feasibility of circumferential pulmonary vein isolation using a novel endoscopic ablation system

Circulation. Arrhythmia and Electrophysiology
Boris SchmidtKarl-Heinz Kuck

Abstract

Pulmonary vein isolation (PVI) is an established treatment option for patients with drug refractory paroxysmal atrial fibrillation. A novel compliant endoscopic ablation system housing a 980-nm-diode laser allows for discrete point-by-point ablation enabling a true circumferential ablation line design. We sought to determine the feasibility and safety of a circumferential ablation using endoscopic ablation system. Thirty patients (17 female; mean age, 58±9 years) with a median paroxysmal atrial fibrillation history of 3 years (range, 1 to 17 years) were treated. PVI was achieved in 114 of 116 (98%) PVs (4 left common PVs), thereby achieving simultaneous PVI for separate ipsilateral PVs in 19 of 26 (73%) left PVs and 6 of 30 (20%) right PVs. The total procedure time was 250±62 minutes. Procedure time decreased from 310±59 to 220±37 minutes (P=0.0001) between the first 10 and the last 20 cases. Mean fluoroscopy time was 30±18 minutes. Twenty-seven patients underwent postoperative endoscopy showing no or minimal thermal lesions in the esophagus in 21 (78%) and 2 (7%), respectively. In 4 (15%) patients, an esophageal ulceration was found that healed without sequelae. One pericardial tamponade and 1 right-sided phrenic nerve palsy o...Continue Reading

References

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Citations

Aug 10, 2011·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Jonathan P Piccini, James P Daubert
Jul 26, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Antonio SorgentePedro Brugada
Nov 19, 2011·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Andreas MetznerKarl-Heinz Kuck
Mar 6, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Hugh CalkinsDavid Wilber
Aug 28, 2013·Nature Reviews. Cardiology·Jane Dewire, Hugh Calkins
Aug 3, 2011·Current Cardiology Reports·Prasanna K Challa, Moussa Mansour
Apr 5, 2012·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Andreas MetznerKarl-Heinz Kuck
Feb 2, 2012·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Srinivas R DukkipatiVivek Y Reddy
Jul 26, 2011·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Fernando M Contreras-ValdesMoussa Mansour
Mar 1, 2011·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Andreas MetznerKarl-Heinz Kuck
Jan 18, 2011·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Andreas MetznerKarl-Heinz Kuck
Jul 15, 2015·Pacing and Clinical Electrophysiology : PACE·Irfan M KhurramSaman Nazarian
Jun 27, 2013·Journal of Cardiovascular Electrophysiology·Stefano BordignonBoris Schmidt
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Sep 13, 2012·Journal of Cardiovascular Electrophysiology·Andreas MetznerKarl-Heinz Kuck
Jan 11, 2012·Journal of Cardiovascular Electrophysiology·Boris SchmidtKr J Chun
Nov 19, 2013·Journal of Cardiovascular Electrophysiology·Erik WissnerKarl-Heinz Kuck
Jul 30, 2014·Journal of Cardiovascular Electrophysiology·Laura PerrottaBoris Schmidt
Jan 15, 2015·Herz·A MetznerK-H Kuck
Nov 13, 2014·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·P GalA Elvan
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Oct 11, 2017·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Hugh CalkinsUNKNOWN Document Reviewers:
Nov 12, 2019·Circulation Journal : Official Journal of the Japanese Circulation Society·Christian-H HeegerRoland Richard Tilz
Apr 24, 2020·Journal of Cardiovascular Electrophysiology·Fabrizio R AssisHarikrishna Tandri
Nov 7, 2012·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Stefano BordignonBoris Schmidt
Oct 4, 2012·Expert Review of Cardiovascular Therapy·Anja SchadeThomas Deneke
May 8, 2018·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Martín R ArceluzJosé L Merino
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Dec 20, 2012·Expert Review of Medical Devices·Josef Kautzner
Mar 14, 2013·Expert Review of Medical Devices·Stefano BordignonBoris Schmidt
Mar 23, 2017·The Journal of Biological Chemistry·Sabine ArndtMichael P Murphy
Nov 21, 2020·JACC. Clinical Electrophysiology·Tilman MaurerKarl-Heinz Kuck
Feb 12, 2021·Circulation. Arrhythmia and Electrophysiology·Boris SchmidtPetr Neuzil
Mar 19, 2021·International Heart Journal·Kaoru OkishigeKenzo Hirao

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