Feasibility of Dose Optimization in a Second-Generation Dual-Source CT Scanner for a Manufacturer-Recommended Urolithiasis Protocol for Imaging Renal Stones

AJR. American Journal of Roentgenology
Michele PansiniSebastian T Schindera

Abstract

The purpose of this article is to investigate the magnitude of dose optimization for a manufacturer-recommended urolithiasis protocol in a second-generation dual-source CT scanner. Custom renal phantoms with 24 stones were scanned using the manufacturer-provided dual-energy CT protocol (tube A, 100 kVp and 210 reference mAs; tube B, 140 kVp and 162 reference mAs) and seven dose-optimized protocols in which the reference tube current-time product setting of tube A was reduced stepwise by 20 mAs. Detection and characterization of the stones was assessed. In the patient study, 25 patients underwent the manufacturer-provided dual-energy protocol and 25 patients underwent imaging with a dose-optimized protocol (tube A, 100 kVp and 90 reference mAs; tube B, 140 kVp and 70 reference mAs). Dose-length product (DLP), image noise, and contrast-to-noise ratio (CNR) were assessed. Subjective image quality was analyzed by three independent radiologists. In the phantom study, the reference tube current-time product of tube A could be reduced from 210 to 90 mAs without losing the accuracy of detection or characterization of the calculi. In the patient study, the dose-optimized protocol resulted in a significant reduction of the average DLP by...Continue Reading

References

Jan 24, 2003·AJR. American Journal of Roentgenology·Denis TackPierre Alain Gevenois
Oct 31, 2006·Seminars in Nephrology·I Alexandru Bobulescu, Orson W Moe
Dec 8, 2006·European Radiology·Thorsten R C JohnsonChristoph R Becker
Mar 23, 2007·AJR. American Journal of Roentgenology·Pierre-Alexandre PolettiChristoph D Becker
Jan 17, 2008·Investigative Radiology·Anno GraserChristoph R Becker
Jul 24, 2008·AJR. American Journal of Roentgenology·Tilo NiemannGeorg Bongartz
May 14, 2010·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Avinash R KambadakoneDushyant V Sahani
Sep 23, 2010·AJR. American Journal of Roentgenology·Giorgio AscentiSilvio Mazziotti
Dec 2, 2011·World Journal of Radiology·Mi Kim SungMannudeep K Kalra
May 25, 2012·AJR. American Journal of Roentgenology·George S K FungBenjamin M W Tsui
Jan 17, 2013·Journal of Computer Assisted Tomography·Naveen M KulkarniDushyant V Sahani

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