Feasibility of Exercise Testing in Patients Who Are Critically Ill: A Prospective, Observational Multicenter Study

Archives of Physical Medicine and Rehabilitation
Juultje SommersMarike van der Schaaf

Abstract

To evaluate the feasibility and safety of exercise testing and to describe the physiological response to exercise of patients in the Intensive Care Unit (ICU). A prospective observational multicenter study. Two mixed medical-surgical ICUs. Patients (N=37; with no primary neurological disorders, 59% men; median age 50y; ICU length of stay 14.5d; Acute Physiology and Chronic Health Evaluation IV 73.0) who had been mechanically ventilated for more than 48 hours and were hemodynamically stable enough to perform physical exercise. A passive or active incremental exercise test, depending on muscle strength, on a bed-based cycle ergometer. Feasibility and safety were evaluated based on protocol adherence and adverse events. Physiological responses to exercise quantified as changes in respiratory frequency (RF), oxygen uptake (Vo2), carbon dioxide output (Vco2), respiratory exchange ratio (RER), and blood lactate. Thirty-seven patients of whom 18 were mechanically ventilated underwent the exercise test. The active incremental test was performed by 28, and the passive test by 9 participants. Thirty-three (89%) accomplished the test according to the protocol and 1 moderate severe adverse event (bradycardia; heart rate 44) occurred shortl...Continue Reading

Citations

May 31, 2019·Current Opinion in Critical Care·Mette M Berger, Claude Pichard
May 12, 2021·Current Opinion in Critical Care·John Whittle, Iñigo San-Millán
Jan 9, 2022·Journal of Cachexia, Sarcopenia and Muscle·Madu N SoaresRob C I Wüst

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