Feasibility of monitoring stress using skin conduction measurements during intubation of newborns

European Journal of Pediatrics
Robin van der LeeRichard A van Lingen

Abstract

The objective of this study was to assess the feasibility of monitoring stress responses in newborns during naso-tracheal intubation after two different premedication regimens, using skin conductance measurements (SCM). Twenty-two newborns were randomised and premedicated with morphine + vecuronium or propofol. SCM (peaks/s) were collected prior to, during and after the procedure. Threshold for interpreting responses as stressful was 0.21 peaks/s. Intubation conditions and physiological parameters were registered. Intubation conditions were good in all newborns. Administration of morphine (range 1.4-10.3 min) before administration of vecuronium did not affect SCM when a stressful stimulus was applied. Within 1.6 min (range 0.8-3 min) after administration of vecuronium, SCM disappeared in 10 of 11 newborns. Propofol reduced SCM in 10 of 11 newborns at the first attempt. Further attempts were associated with increasing SCM, mostly above a threshold of 0.21 peaks/s. There were no significant changes in physiological parameters during the procedure for either premedication regimen. The variation in SCM between individual newborns limits the usefulness of SCM as stress monitor during intubation. The use of neuromuscular blockers for...Continue Reading

References

Oct 5, 1995·Journal of the Autonomic Nervous System·J J VilchesE Verdú
Dec 14, 1996·Journal of the Autonomic Nervous System·V G Macefield, B G Wallin
May 29, 2000·Anesthesia and Analgesia·M F TerRietG J DeSouza
Dec 23, 2000·Archives of Disease in Childhood. Fetal and Neonatal Edition·P Dalla-VorgiaS Reiter-Theil
Nov 21, 2002·Early Human Development·B C Hellerud, H Storm
Sep 5, 2003·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Robert VetrugnoPasquale Montagna
Jul 1, 1962·Proceedings of the Society for Experimental Biology and Medicine·B A SHAVERR E COOKE
Oct 11, 2005·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Vincenzo DonadioRocco Liguori
Oct 12, 2005·The Journal of Comparative Neurology·Eberhard WeiheLee E Eiden
Jul 17, 2007·Neonatology·Sharyn GibbinsArne Ohlsson
Jul 20, 2007·Acta Anaesthesiologica Scandinavica·T Fuchs-BuderUNKNOWN 8th International Neuromuscular Meeting
Dec 6, 2008·Journal of Clinical Epidemiology·Ron SchellingsJ André Knottnerus
Jun 18, 2009·Archives of Disease in Childhood. Fetal and Neonatal Edition·R BellùR Zanini
Jun 24, 2009·British Journal of Anaesthesia·M J Fagerlund, L I Eriksson
Feb 24, 2010·Pediatrics·Praveen KumarUNKNOWN Committee on Fetus and Newborn, Section on Anesthesiology and Pain Medicine
Jul 6, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Luis Pereira-da-SilvaHanne Storm
Aug 10, 2011·Neural Plasticity·Stephen W Briggs, Aristea S Galanopoulou

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Citations

Jul 21, 2017·Archives of Disease in Childhood·Tim J van Hasselt
May 17, 2019·The Clinical Journal of Pain·Jiale HuDenise Harrison
Dec 21, 2018·Neonatal Network : NN·Christopher McPherson
Oct 3, 2021·NeoReviews·Wojciech WalasAndrzej Piotrowski

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