Feasibility of multiple micro-particle trapping--a simulation study

Sensors
Yanyan YuLei Sun

Abstract

Both optical tweezers and acoustic tweezers have been demonstrated for trapping small particles in diverse biomedical applications. Compared to the optical tweezers, acoustic tweezers have deeper penetration, lower intensity, and are more useful in light opaque media. These advantages enable the potential utility of acoustic tweezers in biological science. Since the first demonstration of acoustic tweezers, various applications have required the trapping of not only one, but more particles simultaneously in both the axial and lateral direction. In this research, a method is proposed to create multiple trapping patterns, to prove the feasibility of trapping micro-particles. It has potential ability to electronically control the location and movement of the particles in real-time. A multiple-focus acoustic field can be generated by controlling the excitation of the transducer elements. The pressure and intensity of the field are obtained by modeling phased array transducer. Moreover, scattering force and gradient force at various positions are also evaluated to analyze their relative components to the effect of the acoustic tweezers. Besides, the axial and lateral radiation force and the trapping trajectory are computed based on ...Continue Reading

References

May 1, 1991·The Journal of the Acoustical Society of America·J R Wu
May 13, 1997·Proceedings of the National Academy of Sciences of the United States of America·A Ashkin
Nov 5, 1999·Biophysical Journal·K C NeumanS M Block
Aug 15, 2003·Nature·David G Grier
Jun 17, 2005·The Journal of the Acoustical Society of America·Jungwoo LeeK Kirk Shung
Aug 31, 2006·The Journal of the Acoustical Society of America·Jungwoo Lee, K Kirk Shung
Jan 1, 1989·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·K B Ocheltree, L A Frizzel
Jan 1, 1989·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·E S Ebbini, C A Cain
Mar 4, 2008·Applied and Environmental Microbiology·M B RasmussenH Siegumfeldt
Jun 10, 2010·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Shih-Tsung Kang, Chih-Kuang Yeh
Oct 26, 2010·The Journal of the Acoustical Society of America·C R P CourtneyM Hill
Jan 15, 2011·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Ke Xiao, David G Grier
Jul 12, 2012·Lab on a Chip·Sz-Chin Steven LinTony Jun Huang
Jul 9, 2014·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Shih-Tsung Kang, Chih-Kuang Yeh
Nov 26, 2014·Applied Physics Letters·Ying LiK Kirk Shung

❮ Previous
Next ❯

Methods Mentioned

BETA
optical tweezers
acoustic tweezer
acoustic tweezers

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.