Feasibility of Transabdominal Cardiophrenic Lymphnode Dissection in Advanced Ovarian Cancer: Initial Experience at a Tertiary Center

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
Annalisa GarbiAngelo Maggioni

Abstract

The purpose of this retrospective report is to define the safety and feasibility, based on our preliminary experience, of surgical transdiaphragmatic resection of enlarged cardiophrenic lymph nodes (CPLNs), as a part of upfront debulking surgery. Supradiaphragmatic nodes located between the diaphragm and the heart are frequently a location for lymph node metastasis in advanced ovarian cancer, and their removal is aimed to obtain no gross residual disease at the primary cytoreductive surgery often requiring aggressive surgical procedures. Between May 2012 and October 2016, a total of 22 patients among 443 with advanced high-grade serous ovarian cancer underwent cytoreductive procedures involving transdiaphragmatic resection of enlarged CPLNs at European Institute of Oncology in Milan. All patients who underwent CPLN resection had an extensive disease (median peritoneal cancer index, 18), and more than 77% required complex surgical procedures (complexity score, 3). No residual abdominal disease less than 5 mm at the end of surgery was described in 20 (90%) out of 22. All patients but one had confirmed CPLN positive nodes at histopathological study. The average operative time was 333 min (range, 244-455 min), and the average estim...Continue Reading

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Citations

Jan 15, 2019·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Andre LopesMarcelo Oliveira Dos Santos
Dec 7, 2019·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Ciro PinelliHooman Soleymani Majd
Dec 7, 2019·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Giulio EvangelistiSimone Ferrero
Nov 23, 2019·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Stefania RizzoFilippo Del Grande
Jan 19, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Alyssa LarishWilliam Cilby
Dec 5, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Felix Boria, Luis Chiva

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