Feasibility study for performing uterus transplantation in the Netherlands

Human Reproduction Open
H E PetersW J K Hehenkamp

Abstract

Is it feasible to perform uterus transplantations (UTx) in a tertiary centre in the Netherlands? Considering all ethical principles, surgical risks and financial aspects, we have concluded that at this time, it is not feasible to establish the UTx procedure at our hospital. UTx is a promising treatment for absolute uterine factor infertility. It is currently being investigated within several clinical trials worldwide and has resulted in the live birth of 19 children so far. Most UTx procedures are performed in women with the Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome, a congenital disorder characterized by absence of the uterus. In the Netherlands, the only possible option for these women for having children is adoption or surrogacy. We performed a feasibility study to search for ethical, medical and financial support for performing UTx at the Amsterdam UMC, location VUmc. For this feasibility study, we created a special interest group, including gynaecologists, transplant surgeons, researchers and a financial advisor. Also, in collaboration with the patients' association for women with MRKH, a questionnaire study was performed to research the decision-making in possible recipients. In this paper, we present an overview of ...Continue Reading

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Citations

Jul 13, 2021·The Obstetrician & Gynaecologist : the Journal for Continuing Professional Development From the Royal College of Obstetricians & Gynaecologists·Benjamin P JonesJ Richard Smith

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Methods Mentioned

BETA
dissection
biopsies
hysterectomy

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