Feasibility study of ultrasonic computed tomography-guided high-intensity focused ultrasound

Ultrasound in Medicine & Biology
Haim Azhari

Abstract

The aim of this study was to establish a proof of concept for an ultrasonic image-guided high-intensity focused ultrasound (HIFU) breast treatment system. An ultrasonic computed tomography (UCT) scanner served as a platform for image acquisition and thermal mapping. With this system, images depicting the speed of sound (SOS) can be obtained. After HIFU activation, the resulting changes in SOS can be mapped. For the temperature range T ≤ 45°C, the temperature elevation is obtained directly from the change in SOS. For thermal ablation, monitoring is obtained by studying the temporal derivative of the SOS while continuous HIFU heating is applied. The method was implemented to in vitro tissue specimens and the ability for thermal monitoring was demonstrated. The results indicate that the suggested concept is indeed feasible.

References

Aug 1, 1979·Journal of Clinical Ultrasound : JCU·F W Kremkau
Jan 1, 1979·Ultrasound in Medicine & Biology·J C Bamber, C R Hill
Jun 1, 1984·International Journal of Radiation Oncology, Biology, Physics·S A Sapareto, W C Dewey
Aug 1, 1995·IEEE Transactions on Bio-medical Engineering·R Seip, E S Ebbini
Jul 4, 2002·Journal of the National Cancer Institute·Judith Randal
Dec 7, 2002·Ultrasound in Medicine & Biology·Naomi R MillerPaul M Meaney
Aug 29, 2003·The Journal of the Acoustical Society of America·Tat Hean GanWilliam M D Wright
Sep 23, 2003·The British Journal of Radiology·J E KennedyD Cranston
Jan 18, 2007·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Ajay AnandChristopher Hall
Oct 16, 2007·Ultrasound in Medicine & Biology·Jason W TrobaughEduardo G Moros
Jan 1, 1994·IEEE Transactions on Medical Imaging·H M Hudson, R S Larkin

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Citations

Oct 10, 2013·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Li Xiaoping, Zheng Leizhen
Jul 9, 2014·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Jianguo MaXiaoning Jiang
Oct 2, 2014·Ultrasonic Imaging·Julien RouyerPhilippe Lasaygues
Oct 25, 2017·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Or PerlmanHaim Azhari
Dec 24, 2019·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Daniel Dahis, Haim Azhari

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