Feasibility study to identify women of childbearing age at risk of pregnancy not using any contraception in The Health Improvement Network (THIN) database

BMC Medical Informatics and Decision Making
Lucía Cea SorianoLuis A García Rodríguez

Abstract

Worldwide the rate of unplanned pregnancies is more than 40%. Identifying women at risk of pregnancy can help prevent negative outcomes and also reduce healthcare costs of potential complications. It can also allow the investigation of the natural history of pregnancy outcomes, such as ectopic pregnancies or miscarriages. The use of medical records databases has been a crucial development in the field of pharmacoepidemiology - e.g. The Health Improvement Network (THIN) database is a validated database representative of the UK population. This project aimed to test the feasibility of identifying a population of women of childbearing age who are at risk of pregnancy not using any contraception in THIN database. First a cohort of women of childbearing age (15-45yo) was identified. By applying a computer-based algorithm, containing codes for contraception methods or other suggestion of contraception, the risk of pregnancy was then ascertained. Next, two validation steps were implemented: 1) Revision of medical records/free text and 2) Questionnaires were sent to primary care practitioners (PCP) of women whose medical records had been reviewed. Positive predicted values (PPV) were calculated. A total of 266,433 women were identified...Continue Reading

References

Aug 31, 2006·Pharmacoepidemiology and Drug Safety·Sonia Hernández-Díaz
Oct 27, 2006·Pharmacoepidemiology and Drug Safety·James D LewisBrian L Strom
Oct 22, 2010·Journal of the American Medical Informatics Association : JAMIA·Stephanie J ReisingerJonathan A Morris
Nov 16, 2013·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Lucía Cea SorianoLuis A García-Rodríguez
Aug 21, 2014·The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception·Lucía Cea SorianoLuis Alberto García Rodríguez
Oct 6, 2015·Pharmacoepidemiology and Drug Safety·Lucía Cea SorianoLuis A García Rodríguez
Dec 15, 2015·Pharmacoepidemiology and Drug Safety·Lucía Cea SorianoLuis A García Rodríguez
Aug 18, 2017·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Yu YangSiyan Zhan
Jul 25, 2019·BMC Pregnancy and Childbirth·Ambrogio P LonderoLorenza Driul

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Methods Mentioned

BETA
contraception

Software Mentioned

Gemstrip
Stata

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