Features of Undiagnosed Breast Cancers at Screening Breast MR Imaging and Potential Utility of Computer-Aided Evaluation

Korean Journal of Radiology : Official Journal of the Korean Radiological Society
Mirinae SeoA Jung Chu

Abstract

To retrospectively evaluate the features of undiagnosed breast cancers on prior screening breast magnetic resonance (MR) images in patients who were subsequently diagnosed with breast cancer, as well as the potential utility of MR-computer-aided evaluation (CAE). Between March 2004 and May 2013, of the 72 consecutive pairs of prior negative MR images and subsequent MR images with diagnosed cancers (median interval, 32.8 months; range, 5.4-104.6 months), 36 (50%) had visible findings (mean size, 1.0 cm; range, 0.3-5.2 cm). The visible findings were divided into either actionable or underthreshold groups by the blinded review by 5 radiologists. MR imaging features, reasons for missed cancer, and MR-CAE features according to actionability were evaluated. Of the 36 visible findings on prior MR images, 33.3% (12 of 36) of the lesions were determined to be actionable and 66.7% (24 of 36) were underthreshold; 85.7% (6 of 7) of masses and 31.6% (6 of 19) of non-mass enhancements were classified as actionable lesions. Mimicking physiologic enhancements (27.8%, 10 of 36) and small lesion size (27.8%, 10 of 36) were the most common reasons for missed cancer. Actionable findings tended to show more washout or plateau kinetic patterns on MR...Continue Reading

References

Feb 1, 1997·AJR. American Journal of Roentgenology·C E SoderstromD P Flamig
Aug 6, 2002·Breast Cancer Research and Treatment·P BelliG Pastore
Jul 30, 2004·The New England Journal of Medicine·Mieke KriegeUNKNOWN Magnetic Resonance Imaging Screening Study Group
Sep 16, 2004·JAMA : the Journal of the American Medical Association·Ellen WarnerSteven A Narod
Nov 19, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christiane K KuhlHans H Schild
Mar 30, 2007·CA: a Cancer Journal for Clinicians·Debbie SaslowUNKNOWN American Cancer Society Breast Cancer Advisory Group
Feb 7, 2008·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Shin Ho LeeWoo Kyung Moon
Aug 22, 2009·AJR. American Journal of Roentgenology·Lilian C WangConstance D Lehman
Oct 31, 2009·Breast Cancer Research and Treatment·Inge-Marie A ObdeijnCarla Boetes
Dec 24, 2010·AJR. American Journal of Roentgenology·Niamh M HamblyElizabeth A Morris
Mar 28, 2012·AJR. American Journal of Roentgenology·Wendy B DeMartiniConstance D Lehman
Apr 24, 2012·Radiology·Emmanuelle Bouic PagesPatrice Taourel
May 17, 2012·Radiology·Mary C MahoneyConstance Lehman
May 25, 2013·AJR. American Journal of Roentgenology·Constance D LehmanMitchell D Schnall
Jun 8, 2013·European Journal of Radiology·Astrid BaurKatja C Siegmann-Luz

❮ Previous
Next ❯

Citations

Jan 18, 2017·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Mirinae SeoKyu-Yeoun Won
May 2, 2017·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Shuang-Qing ChenChuan-Xiao Xu
Sep 4, 2018·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jung-Hyun KangEun Ju Son
Mar 20, 2021·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Katrina E KorhonenEmily F Conant

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
biopsies
for

Software Mentioned

Picture Archiving and Communication System ( PACS )
CADSTREAM
SPSS

Related Concepts

Related Feeds

Cancer Imaging

Imaging techniques, including CT and MR, have become essential to tumor detection, diagnosis, and monitoring. Here is the latest research on cancer imaging.