Abstract
Virchow-Robin spaces (VRSs) are perivascular pia-lined extensions of the subarachnoid space around the arteries and veins as they enter the brain parenchyma. These spaces are responsible for inflammatory processes within the brain. This study was designed to shed more light on the location, size and shape of VRSs on 3mm slice thickness, 1.5 Tesla MRI scans of newly diagnosed MS patients in Isfahan, Iran and compare the results with healthy age- and sex-matched controls. We evaluated MRI scans of 73 MS patients obtained within 3 months of MS onset and compared them with MRI scans from 73 age- and sex-matched healthy volunteers. Three mm section proton density, T2W and FLAIR MR images were obtained for all subjects. The location, size and shape of VRSs were compared between the two groups. The total number of VRSs was significantly more in the MS group (p<0.001). The distribution of VRSs were significantly more located in the high convexity areas in the MS group (p<0.001), while there was no significant differences in other regions. The round shaped VRSs were significantly more detected on MRI scans of MS patients, and curvilinear shapes were significantly more frequently observed in healthy volunteers, however there were no sign...Continue Reading
References
Jan 1, 1991·AJR. American Journal of Roentgenology·A D Elster, D N Richardson
Oct 1, 1988·Radiology·C A JungreisJ Moossy
Sep 1, 1986·Journal of Neurosurgery·M Hutchings, R O Weller
Jun 6, 2007·Multiple Sclerosis : Clinical and Laboratory Research·A H MaghziA Hassanzadeh
Jul 11, 2007·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Robert M Kwee, Thomas C Kwee
Aug 28, 2009·Journal of the Neurological Sciences·Franz FazekasSiegrid Fuchs
Nov 1, 1978·Applied Optics·J Duvernoy
Citations
Sep 13, 2011·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Satoshi TsutsumiIkuko Ogino
Jul 31, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Burcak BilginerNejat Akalan
Dec 4, 2013·La Radiologia medica·Renata ConfortiSossio Cirillo
May 9, 2015·NeuroImage·Yu-Rong GaoPatrick J Drew
Sep 30, 2015·Journal of Neuroscience Methods·Xin WangJoanna M Wardlaw
Feb 27, 2013·Journal of Magnetic Resonance Imaging : JMRI·Maria del C Valdés HernándezJoanna M Wardlaw
Sep 1, 2016·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Xin WangJoanna M Wardlaw
Jul 18, 2016·Neuroradiology·Renata ConfortiSossio Cirillo
Jul 12, 2014·Multiple Sclerosis : Clinical and Laboratory Research·I D KilsdonkM P Wattjes
May 31, 2015·Cephalalgia : an International Journal of Headache·Andreas Kattem HusøyLars Jacob Stovner
Mar 24, 2016·PloS One·Asaff HarelMatilde Inglese
Mar 28, 2017·AJNR. American Journal of Neuroradiology·J GutierrezC B Wright
Mar 10, 2018·Nature Reviews. Neurology·Ruth GeraldesUNKNOWN MAGNIMS study group
Apr 28, 2012·Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre·Osama Al-SaeedMehraj Sheikh
Apr 1, 2017·IEEE Transactions on Bio-medical Engineering·Jun ZhangDinggang Shen
Oct 19, 2017·PloS One·Alice FavarettoPaolo Gallo
May 7, 2020·Frontiers in Neuroanatomy·Fernanda TroiliMichele Cavallari
Oct 5, 2017·Scientific Reports·Mari MiyataYukunori Korogi
Dec 12, 2017·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Michele CavallariCharles R G Guttmann
Sep 3, 2019·Frontiers in Neurology·Xin WangXingquan Zhao
Jun 15, 2020·Journal of Neurology·Tobias GranbergBenjamin V Ineichen
Nov 6, 2020·Journal of Theoretical Biology·Nicolae Moise, Avner Friedman
Oct 29, 2020·Multiple Sclerosis Journal - Experimental, Translational and Clinical·Lindsey WooliscroftRebecca Spain