Febrile morbidity following hysterosalpingography: identification of risk factors and recommendations for prophylaxis

Fertility and Sterility
P G Stumpf, C M March

Abstract

Although previous large series have reported that from 0.3% to 1.3% of patients undergoing hysterosalpingography (HSG) develop infectious morbidity, our impression was that the incidence was higher among our patients. Therefore the records of 448 consecutive healthy women who underwent HSG were examined. Within 24 hours after the HSG, 14 of these 448 patients (3.1%) developed fever and pelvic peritonitis requiring hospitalization and treatment with parenteral antibiotics, a significantly greater frequency than reported elsewhere (P less than 0.01). Traditional laboratory tests failed to predict patients at risk, and prophylactic antibiotics effective against aerobic organisms could not protect against this complication. However, it was possible to design a scoring system based on specific findings in the history and previous physical examinations that was capable of identifying patients who would subsequently become infected. The clinical sensitivity of this scoring technique is 57%, clinical specificity 99%, and test efficiency 97%. It is suggested that in view of the major risk of post-HSG infection in certain identifiable women and because of the impact of this complication on their future fertility, hysterosalpingography sh...Continue Reading

Associated Clinical Trials

Citations

Aug 1, 2014·Australasian Journal of Ultrasound in Medicine·Rachael RodgersChristopher Benness
Apr 1, 1988·British Journal of Obstetrics and Gynaecology·R J PyperE T Houang
Dec 22, 1999·Human Reproduction·S Macmillan, A Templeton
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Jun 4, 2013·The Cochrane Database of Systematic Reviews·Jadsada ThinkhamropPisake Lumbiganon
Jan 1, 1989·Urologic Radiology·R L Clark, B Keefe
Jan 25, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·Spyros PapaioannouArri Coomarasamy
Jan 4, 2020·Abdominal Radiology·Aoife KilcoyneSusanna I Lee
Aug 12, 2021·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Ruya DeveerAkin Sivaslioglu

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