Fecal microbiota profile in atopic asthmatic adult patients

European Annals of Allergy and Clinical Immunology
A M OkbaD A Mohamed

Abstract

Background. Studies proposed a link between gut microbiota and airway tract.Objective.Study the diversity and density of gut microbiota in healthy and asthmatic patients.Method.Semi-quantitative stool cultures were performed from fecal samples collected from 80 adult asthmatic patients and 40 healthy individuals. Data on gender, age, dietetic history, clinical examination and investigations as skin prick test and pulmonary function testing were also collected.Results.Lactobacilliwere found to be higher among patient group than control group.E. colidensity was statistically higher in patient than control group. No significant difference was detected between male and female patients or controls.Lactobacilliwere statistically more prevalent in stool culture of male cases than that of male controls. No difference was found between female cases and controls. There was no relationship between type of microbial growth and disease related parameters including age, duration of illness, number of allergens and pulmonary function test in cases.Conclusion.Atopic asthma is significantly associated with gut microbiotaLactobacilliandE. coli. It is important to determine the organism involved, to focus on microbiome-driven disease and therapies.

Citations

Dec 4, 2019·Scandinavian Journal of Immunology·Mohammad SalamehDalia Zakaria
Apr 24, 2021·International Journal of General Medicine·Aisha Alamri

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