Fecal triiodothyronine and thyroxine concentrations change in response to thyroid stimulation in Steller sea lions (Eumetopias jubatus)

General and Comparative Endocrinology
A L KeechSamuel K Wasser

Abstract

Variation in concentrations of thyroid hormones shed in feces may help to identify physiological states of animals, but the efficacy of the technique needs to be validated for each species. We determined whether a known physiological alteration to thyroid hormone production was reflected in hormone concentrations in the feces of Steller sea lions (Eumetopias jubatus). We quantified variation of triiodothyronine (T3) and thyroxine (T4) concentrations in feces following two intramuscular injections of thyrotropin (thyroid-stimulating hormone, TSH) at 24h intervals in four captive female sea lions. We found fecal T3 concentrations increased 18-57% over concentrations measured in the baseline sample collected closest to the time of the first TSH injection (p=0.03) and 1-75% over the mean baseline concentration (p=0.12) for each animal of all samples collected prior to injections. Peak T3 concentrations were greater than the upper bound of the baseline 95% confidence interval for three animals. The peak T3 response occurred 48h post-injection in three animals and 71h in the fourth. Post-injection T4 concentrations did not differ between the baseline sample collected closest to the time of the first TSH injection (p=0.29) or the mean...Continue Reading

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Citations

Apr 24, 2010·General and Comparative Endocrinology·Samuel K WasserErnesto Rodríguez-Luna
May 7, 2014·General and Comparative Endocrinology·David C Kersey, Martin Dehnhard
Apr 29, 2015·Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology·Shannon AtkinsonKendall Mashburn
May 1, 2021·Animals : an Open Access Journal From MDPI·Maria Chmurska-GąsowskaŁukasz Migdał

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