PMID: 2112636May 1, 1990Paper

Feeding the rat intravenously with ketone bodies following colon anastomosis

JPEN. Journal of Parenteral and Enteral Nutrition
M NagayamaR H Birkhahn

Abstract

Ketone bodies are an important metabolic fuel for the gastrointestinal system and as a consequence may promote colonic healing. Ketone bodies and glucose were compared in a dose dependent manner as nonprotein fuels for support of resected colon. Rats had their descending colons resected and received all nutrients by vein for 5 days postoperation. Colonic healing was evaluated from the air pressure required to break the wound. All rats received constant nutrients except for non-protein energy which was fed at 10.5, 21, 31.5, and 42 kcal/day using either glucose or monoacetoacetin as substrate. Colonic bursting pressure was measured on day 5 after surgery. When energy intake was 21 kcal/day or greater, the bursting pressure was two-thirds of nonwounded tissue and was independent of energy quantity and source. At 10.5 kcal/day, bursting pressure for glucose-fed animals was similar to that for animals with no added nonprotein energy while, in contrast, bursting pressure for animals fed monoacetoacetin was similar to that for animals fed 42 kcal/day. It was concluded that bursting pressure was influenced by dietary intake only if the energy intake was sufficiently low, and then ketone bodies were better than glucose for support of c...Continue Reading

References

Mar 1, 1978·The American Journal of Clinical Nutrition·R H Birkhahn, J R Border
May 1, 1979·The Journal of Dermatologic Surgery and Oncology·S V Pollack
Aug 1, 1979·The Journal of Dermatologic Surgery and Oncology·S V Pollack
Nov 1, 1989·The Journal of Surgical Research·R H BirkhahnN R Thomford
May 1, 1986·The Journal of Nutrition·R H BirkhahnN R Thomford
Feb 1, 1988·The Journal of Surgical Research·R H BirkhahnN R Thomford
Apr 1, 1988·The Journal of Surgical Research·S A KripkeR G Settle
Feb 15, 1985·The Biochemical Journal·A MaizG L Blackburn
Nov 1, 1985·The Biochemical Journal·M S Ardawi, E A Newsholme
Nov 1, 1974·Annals of Surgery·T T Irvin, T K Hunt
Jan 1, 1980·Physiological Reviews·A M Robinson, D H Williamson
Jul 1, 1981·JPEN. Journal of Parenteral and Enteral Nutrition·G F Cahill

❮ Previous
Next ❯

Citations

Jun 1, 1997·The Surgical Clinics of North America·F J Thornton, A Barbul

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Surgical Research. Europäische Chirurgische Forschung. Recherches Chirurgicales Européennes
W J MastboomH H de Boer
Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society
M H VerhofstadT Hendriks
The Journal of Surgical Research
R H BirkhahnN R Thomford
© 2021 Meta ULC. All rights reserved