FEF TMS affects visual cortical activity

Cerebral Cortex
Paul C J TaylorMatthew F S Rushworth

Abstract

We tested whether the frontal eye field (FEF) is critical in controlling visual processing in posterior visual brain areas during the orienting of spatial attention. Short trains (5 pulses at 10 Hz) of transcranial magnetic stimulation (TMS) were applied to the right FEF during the cueing period of a covert attentional task while event-related potentials (ERPs) were simultaneously recorded from lateral posterior electrodes, where visual components are prominent. FEF TMS significantly affected the neural activity evoked by visual stimuli, as well as the ongoing neural activity recorded during earlier anticipation of the visual stimuli. The effects of FEF TMS started earlier and were greatest for brain activity recorded ipsilaterally to FEF TMS and contralaterally to the visual stimulus. The TMS-induced effect on visual ERPs occurred at the same time as ERPs were shown to be modulated by visual attention. Importantly, no similar effects were observed after TMS of a control site that was physically closer but not anatomically interconnected to the recording sites. The results show that the human FEF has a causal influence over the modulation of visual activity in posterior areas when attention is being allocated.

Citations

Dec 17, 2009·Brain Topography·Risto J Ilmoniemi, Dubravko Kicić
Apr 18, 2012·Cerebral Cortex·Ana B ChicaPaolo Bartolomeo
Mar 31, 2007·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Patrik Vuilleumier, Jon Driver
Jan 19, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Steven L PrimeJ Douglas Crawford
Aug 14, 2009·Journal of Neurophysiology·Jeremiah Y CohenGeoffrey F Woodman
Oct 16, 2009·Journal of Neurophysiology·Ilya E Monosov, Kirk G Thompson
Jun 23, 2007·Journal of Cognitive Neuroscience·Jacinta O'SheaVincent Walsh
Feb 10, 2009·Journal of Cognitive Neuroscience·Debora BrignaniAnna Christina Nobre
Mar 24, 2009·Journal of Cognitive Neuroscience·Keith J DuncanJoseph T Devlin
May 15, 2013·Journal of Cognitive Neuroscience·Marjan Persuh, Tony Ro
Aug 3, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Simone VosselGereon R Fink
May 8, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Paolo CapotostoMaurizio Corbetta
Nov 2, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Taraz G Lee, Mark D'Esposito
Aug 28, 2009·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Leeland B EkstromWim Vanduffel
Oct 11, 2012·Cerebral Cortex·Luca RonconiAndrea Facoetti
Nov 28, 2012·Cerebral Cortex·Stéphanie M MorandMarie-Hélène Grosbras
Nov 22, 2013·ISRN Neurology·Jeffrey D Schall
May 23, 2007·Proceedings of the National Academy of Sciences of the United States of America·Katherine M Armstrong, Tirin Moore
Jun 16, 2014·Nature Neuroscience·Georgia G GregoriouRobert Desimone
Oct 11, 2013·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Theodore P ZantoAdam Gazzaley
Jan 7, 2016·Frontiers in Systems Neuroscience·Elizabeth S LorencMark D'Esposito
Sep 22, 2015·Frontiers in Systems Neuroscience·Michael J WolffMark G Stokes
Sep 23, 2014·Journal of Cognitive Neuroscience·Magdalena W SliwinskaJoseph T Devlin
Jun 7, 2016·Current Biology : CB·Laura DuguéMarisa Carrasco
Sep 30, 2016·Frontiers in Human Neuroscience·Stavros I DimitriadisAnastasios Bezerianos

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.