Feline conjunctival melanoma: histopathological characteristics and clinical outcomes

Veterinary Ophthalmology
Charles SchobertR R Dubielzig

Abstract

We report on the histopathology and clinical features of 21 cases of feline conjunctival melanoma. A total of 18 cases are from the COPLOW collection and three cases from Antech Diagnostics. We tabulated the location of the tumor, pigmentation, cell shape, mitotic index and presence of multinucleated tumor cells. Surveys were sent to referring ophthalmologists to obtain further information about each case. The mean age of the cats was 12.4 years. A total of 11 cases were neutered males, six spayed females, and one each of intact female and male. Thirteen of the 21 cases were located on the bulbar conjunctiva, three on third eyelid only, three on palpebral conjunctiva. Sixteen tumors were pigmented while five were amelanotic. Seventeen of the cases consisted of round cell only while four cases were mixed populations of round and spindle cell. Fourteen of the cases contained multinucleated cells. The mitotic index ranged from 0 to 45 mitotic figures/10 HPF. Of the 13 cases with adequate follow-up information, four showed local recurrence while three reported metastasis. Eight cats had died at the time of the survey. Survival time post-diagnosis ranged from 0.5 to 36 months. Two cases had metastasized to the submandibular lymph no...Continue Reading

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Citations

Jun 28, 2011·Journal of Feline Medicine and Surgery·Michelle A Morges, Karen Zaks
Jun 12, 2013·Veterinary Ophthalmology·Caroline J Zeiss
Apr 2, 2015·Veterinary Ophthalmology·D Dustin DeesTimothy J Stein
Sep 10, 2014·Veterinary Ophthalmology·Dustin D DeesNicole E MacLaren
May 8, 2016·Topics in Companion Animal Medicine·Annie L Wang, Thomas Kern
Dec 20, 2015·Journal of Feline Medicine and Surgery·Luminita SarbuPhilip J Bergman

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