Feline discrete high-grade gastrointestinal lymphoma treated with surgical resection and adjuvant CHOP-based chemotherapy: retrospective study of 20 cases

Veterinary and Comparative Oncology
E D GouldinCraig A Clifford

Abstract

The aim of this retrospective study was to evaluate the outcome of cats treated with surgical intervention for a discrete intermediate-/high-grade gastrointestinal lymphoma prior to CHOP-based chemotherapy. Variables including sex, breed, haematocrit, white blood cell count, serum albumin concentration, clinical stage of disease, gastrointestinal obstruction and peritonitis were assessed for their effect on survival. Twenty cats met the inclusion criteria with three cats still alive at the time of data analysis. The overall median survival time (MST) was 417 days (range: 12-2962 days). The disease-free interval (DFI) was 357 days (range: 0-1585 days) with six cats still deemed in remission prior to death. Only clinical stage had a significant effect on both MST and DFI. Cats with discrete intermediate/high-grade gastrointestinal lymphoma that undergo surgical resection followed by adjuvant CHOP chemotherapy may achieve acceptable overall survival times.

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Citations

Sep 1, 2016·Journal of Feline Medicine and Surgery·Birgitt WolfesbergerAndrea Fuchs-Baumgartinger
Aug 16, 2017·Journal of Feline Medicine and Surgery·Zachary CrouseLinda Kidd
Feb 20, 2019·Veterinary Medicine and Science·Michael MorriceSam Beck
Mar 13, 2019·Veterinary Medicine and Science·Michael MorriceSam Beck
May 19, 2020·Journal of Feline Medicine and Surgery·Luís M Corrêa, Jackie L Demetriou
Oct 12, 2018·BMC Veterinary Research·Mathieu V PaulinValérie Freiche
Feb 3, 2018·Journal of the American Veterinary Medical Association·Naoko SogameKristine E Burgess
Aug 31, 2020·The Journal of Veterinary Medical Science·Makoto AkiyoshiMasami Akiyoshi
Jan 20, 2021·Journal of Feline Medicine and Surgery·Ashlyn G WilliamsKenneth E Lamb
Mar 2, 2021·Journal of Feline Medicine and Surgery·Changseok KimEsther Chon
Apr 4, 2021·Animals : an Open Access Journal From MDPI·Paola ValentiGiancarlo Avallone
Apr 7, 2021·The Journal of Small Animal Practice·S Marsilio

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