Feline immunodeficiency virus cell entry

Journal of Virology
S C FreyJ I Mullins

Abstract

The process of feline immunodeficiency virus (FIV) cell entry was examined using assays for virus replication intermediates. FIV subtype B was found to utilize the chemokine receptor CXCR4, but not CCR5, as a cellular receptor. Zidovudine blocked formation of late viral replication products most effectively, including circular DNA genome intermediates. Our findings extend the role of CXCR4 as a primary receptor for CD4-independent cell entry by FIV.

References

Aug 11, 1992·Journal of Virology·F LoriR C Gallo
Jun 1, 1991·Journal of Virology·W C BrownE W Collisson
Dec 1, 1991·Journal of Virology·C M Farnet, W A Haseltine
Oct 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·R A OlmstedP R Johnson
Mar 1, 1995·Veterinary Immunology and Immunopathology·J B RottmanM B Tompkins
Sep 1, 1993·Journal of Virology·R V EnglishM B Tompkins
Sep 26, 1997·Leukemia·A Cara, M S Reitz

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Citations

Feb 16, 2007·Australian Veterinary Journal·M J Hosie, J A Beatty
Dec 27, 2013·Biochimica Et Biophysica Acta·Mario ScrimaAnna Maria D'Ursi
Sep 22, 2018·PloS One·Manuela GrimaldiAnna Maria D'Ursi
Mar 20, 2020·International Journal of Molecular Sciences·Manuela GrimaldiAnna Maria D'Ursi

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