Feline immunodeficiency virus (FIV) in wild Pallas' cats.

Veterinary Immunology and Immunopathology
Meredith A BrownStephen J O'Brien

Abstract

Feline immunodeficiency virus (FIV), a feline lentivirus related to HIV, causes immune dysfunction in domestic and wild cats. The Pallas' cat is the only species from Asia known to harbor a species-specific strain of FIV designated FIV(Oma) in natural populations. Here, a 25% seroprevalence of FIV is reported from 28 wild Mongolian Pallas' cats sampled from 2000 to 2008. Phylogenetic analysis of proviral RT-Pol from eight FIV(Oma) isolates from Mongolia, Russia, China and Kazakhstan reveals a unique monophyletic lineage of the virus within the Pallas' cat population, most closely related to the African cheetah and leopard FIV strains. Histopathological examination of lymph node and spleen from infected and uninfected Pallas' cats suggests that FIV(Oma) causes immune depletion in its' native host.

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Citations

Dec 27, 2011·Trends in Genetics : TIG·Robert J Gifford
Nov 2, 2011·The Veterinary Clinics of North America. Small Animal Practice·Joanna WhiteJacqueline M Norris
Jul 12, 2011·Veterinary Immunology and Immunopathology·Reinhard ErtlDieter Klein
Jul 5, 2011·Veterinary Immunology and Immunopathology·Jennifer L TroyerStephen J O'Brien
May 17, 2012·Viruses·Bruno M TeixeiraMargaret J Hosie
Dec 14, 2019·Transboundary and Emerging Diseases·John LewisOlga Uphyrkina
Mar 27, 2020·Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians·Simon J GirlingDavid Barclay
Jun 2, 2021·EcoHealth·Daan J E LoockLourens H Swanepoel

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