Feline vaccine-associated fibrosarcoma induced by aluminium compound in two cats: short communication

Acta Veterinaria Hungarica
Zoltán DeimGábor Cserni

Abstract

Two cases of feline vaccine-associated fibrosarcoma (FVAF) are reported. The excised tumours were both characterised as well circumscribed, subcutaneous, firm and white with central necrosis. Histopathologically, they consisted of well-differentiated and variably sized and shaped anaplastic cells, characterised by marked nuclear and cellular pleomorphism including giant cells. The mitotic activity was low. Aluminium was demonstrated in the central necrosis and giant cells. Neoplastic cells were positive for vimentin and negative for desmin and cytokeratin. The presence of feline sarcoma virus and feline immunodeficiency virus could not be detected by PCR in either case.

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Citations

Aug 25, 2012·Journal of the American Veterinary Medical Association·Anup SrivastavMichael S Kent
Sep 18, 2016·Clinics in Dermatology·Stefano CaccavaleEleonora Ruocco
Jun 24, 2015·Journal of Feline Medicine and Surgery·Katrin HartmannUNKNOWN European Advisory Board on Cat Diseases
May 24, 2018·Journal of Feline Medicine and Surgery·Carolina S CarneiroJulia M Matera
Sep 30, 2017·Veterinary and Comparative Oncology·M A AbdelMageedE A McNiel
Jun 11, 2017·Vaccine·Ravendra GargVolker Gerdts

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