Felis catus papillomavirus types 1 and 4 are rarely present in neoplastic and inflammatory oral lesions of cats

Research in Veterinary Science
J S Munday, Adrienne F French

Abstract

Oral squamous cell carcinomas (OSCCs) are common feline cancers. Why OSCCs are so common in cats is unknown; however, 25% of human OSCCs are caused by papillomaviruses (PVs). Two feline oral PVs (FcaPV-1 and 4) are recognized. As PVs are highly host and location specific, if PVs do cause feline OSCCs, FcaPV-1 and 4 are the most likely etiological agents. PCR primers specific for FcaPV-1 amplified DNA from 1 of 36 feline OSCCs and 1 of 16 inflammatory oral lesions. No DNA was amplified by primers specific for FcaPV-4. PV DNA was not amplified from any additional sample using consensus primers. No PV cytopathology was visible in the OSCC that contained FcaPV-1 DNA, but viral cytopathology was present in a focus of epithelial hyperplasia in the non-neoplastic sample. This study does not support a PV etiology of feline OSCCs, but shows that FcaPV-1 can asymptomatically infect the mouth of cats.

References

Jan 22, 2000·Veterinary Pathology·J P SundbergA B Jenson
Jul 6, 2007·Veterinary Dermatology·John S MundayRichard A Squires
Aug 22, 2008·Research in Veterinary Science·J S MundayH Sugiarto
Jul 9, 2010·Veterinary Dermatology·Sarah H O'NeillStephen A Kania

❮ Previous
Next ❯

Citations

Sep 13, 2016·Transboundary and Emerging Diseases·R M Gil da CostaD DiMaio
Jun 8, 2018·The Journal of Veterinary Medical Science·Nanako Yamashita-KawanishiTakeshi Haga
Sep 22, 2018·Oncotarget·Hunter John PiegolsVilma Yuzbasiyan-Gurkan
Jun 30, 2015·Veterinary Sciences·Claire M Cannon
Aug 15, 2018·Veterinary Sciences·Walaa Hamed Shaker NasryChelsea K Martin
Nov 10, 2020·Frontiers in Microbiology·Gennaro AltamuraGiuseppe Borzacchiello
Aug 29, 2021·Viruses·John S Munday, Neroli A Thomson
Aug 31, 2021·Critical Reviews in Oncology/hematology·Roberto GrigolatoLuca Calabrese

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
J S MundayLaryssa Howe
Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
J S Munday, J Peters-Kennedy
© 2021 Meta ULC. All rights reserved