Female migraineurs show lack of insular thinning with age

Pain
Nasim MalekiDavid Borsook

Abstract

Gray matter loss in cortical regions is a normal ageing process for the healthy brain. There have been few studies on the process of ageing of the brain in chronic neurological disorders. In this study, we evaluated changes in the cortical thickness by age in 92 female subjects (46 patients with migraine and 46 healthy controls) using high-field magnetic resonance imaging. The results indicate that in contrast to healthy subjects, migraineurs show a lack of thinning in the insula by age. The functional significance of the lack of thinning is unknown, but it may contribute to the overall cortical hyperexcitability of the migraine brain because the region is tightly involved in a number of major brain networks involved in interoception, salience, nociception, and autonomic function, including the default mode network.

References

Aug 1, 1988·Headache·H Havanka-KanniainenV V Myllylä
May 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·S D FormanD C Noll
Sep 14, 2000·Proceedings of the National Academy of Sciences of the United States of America·B Fischl, A M Dale
Apr 11, 2001·Lancet·A BahraP J Goadsby
Jul 11, 2001·Neurobiology of Aging·T L JerniganJ R Hesselink
Sep 11, 2001·Psychological Bulletin·T Pincus, S Morley
Jan 28, 2003·Nature Neuroscience·Elizabeth R SowellArthur W Toga
Sep 11, 2003·Current Opinion in Neurobiology·A D Craig
Feb 26, 2004·Cephalalgia : an International Journal of Headache·UNKNOWN Headache Classification Subcommittee of the International Headache Society
Jun 29, 2004·NeuroImage·F SégonneB Fischl
Oct 27, 2004·NeuroImage·Bruce FischlAnders M Dale
Nov 19, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·A Vania ApkarianDarren R Gitelman
Feb 12, 2005·Brain : a Journal of Neurology·S K AfridiP J Goadsby
Apr 27, 2005·Human Brain Mapping·Stuart M GrieveEvian Gordon
Jan 10, 2006·Brain : a Journal of Neurology·Andrea E Cavanna, Michael R Trimble
Jul 14, 2006·Menopause : the Journal of the North American Menopause Society·Marina BoccardiGiovanni B Frisoni
Sep 21, 2006·Brain : a Journal of Neurology·Foucaud du BoisgueheneucBruno Dubois
Oct 7, 2006·Neurobiology of Aging·Osamu AbeKuni Ohtomo
Mar 30, 2007·Brain : a Journal of Neurology·Ingrid R OlsonYoussef Ezzyat
Apr 13, 2007·IEEE Transactions on Medical Imaging·Florent SégonneBruce Fischl
Jul 17, 2007·Neurobiology of Aging·Grégoria KalpouzosBéatrice Desgranges
Nov 8, 2007·Cephalalgia : an International Journal of Headache·T Schmidt-WilckeA May
Nov 21, 2007·Neurology·Alexandre F M DaSilvaNouchine Hadjikhani
Jan 11, 2008·Headache·Walter ValfrèLorenzo Pinessi
Apr 22, 2008·Cephalalgia : an International Journal of Headache·J H KimS-B Koh
May 16, 2008·Headache·Nicole SchmitzMark A van Buchem
Jun 17, 2008·Neuroscience Letters·Nicole SchmitzMark A van Buchem
Nov 20, 2008·Journal of Neuropathology and Experimental Neurology·Stefanie H FreemanBradley T Hyman
Dec 20, 2008·Nature Reviews. Neuroscience·A D Bud Craig
Mar 14, 2009·Neurobiology of Aging·Débora TerribilliGeraldo F Busatto
Mar 24, 2009·Neuroscience·P J GoadsbyP R Holland
May 19, 2009·Lancet Neurology·Todd J Schwedt, David W Dodick
Jun 6, 2009·Cephalalgia : an International Journal of Headache·J H KimK Oh
Nov 10, 2009·Neuroscience and Biobehavioral Reviews·Stefaan Van DammeGeert Crombez
Jun 1, 2010·Brain Structure & Function·Vinod Menon, Lucina Q Uddin
Jun 1, 2010·Brain Structure & Function·Agustin IbañezFacundo Manes
Jun 17, 2010·Brain Research·Belinda PletzerHubert H Kerschbaum

❮ Previous
Next ❯

Citations

Mar 29, 2016·Seminars in Pediatric Neurology·Nasim MalekiAlison Field
May 18, 2016·Current Neurology and Neuroscience Reports·Catherine D ChongDavid W Dodick
Jul 5, 2016·Frontiers in Neurology·Paul M MaceyRonald M Harper
Jul 9, 2016·Expert Review of Neurotherapeutics·Carlo LovatiClaudio Mariani
Jul 19, 2016·Neuroscience and Biobehavioral Reviews·Joukje M Oosterman, Dieuwke S Veldhuijzen
Nov 5, 2016·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·David BorsookLino Becerra
Apr 18, 2020·Cephalalgia : an International Journal of Headache·Kuan-Lin LaiShuu-Jiun Wang
Jan 12, 2019·The Journal of Headache and Pain·Hedvig KomáromyZoltán Pfund
Dec 12, 2018·Cephalalgia : an International Journal of Headache·Stefano MagonTill Sprenger
Feb 13, 2020·Frontiers in Neurology·Catherine D Chong
Feb 28, 2019·BioMed Research International·Masahiko AyakiKazuno Negishi
Sep 26, 2019·Frontiers in Neurology·Nasim Maleki, Xiao Michelle Androulakis
May 26, 2017·Scientific Reports·Chih-Hao ChenYen-Ching Chen
Nov 22, 2016·Journal of Neuroscience Research·Jelena M PavlovicNasim Maleki
Mar 7, 2019·Cephalalgia : an International Journal of Headache·Fleur LereboursNelly Fabre
Jan 26, 2021·Frontiers in Neuroscience·LiQin ShengPingLei Pan
May 27, 2021·Current Pain and Headache Reports·Ching-Mao ChangShuu-Jiun Wang
Jun 5, 2021·NeuroImage. Clinical·Peter Shih-Ping HungMojgan Hodaie

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Aging

Here is the latest research on intrinsic and extrinsic factors, as well as pathways and mechanisms that underlie aging in the central nervous system.