Female patients with low systemic BMD are prone to bone loss in Gruen zone 7 after cementless total hip arthroplasty.

Acta Orthopaedica
Jessica J AlmHannu T Aro

Abstract

Factors that lead to periprosthetic bone loss following total hip arthroplasty (THA) may not only depend on biomechanical implant-related factors, but also on various patient-related factors. We investigated the association between early changes in periprosthetic bone mineral density (BMD) and patient-related factors. 39 female patients underwent cementless THA (ABG II) with ceramic-ceramic bearing surfaces. Periprosthetic BMD in the proximal femur was determined with DXA after surgery and at 3, 6, 12, and 24 months. 27 patient-related factors were analyzed for their value in prediction of periprosthetic bone loss. Total periprosthetic BMD was temporarily reduced by 3.7% at 3 months (p < 0.001), by 3.8% at 6 months (p < 0.01), and by 2.6% at 12 months (p < 0.01), but recovered thereafter up to 24 months. Preoperative systemic osteopenia and osteoporosis, but not the local BMD of the operated hip, was predictive of bone loss in Gruen zone 7 (p = 0.04), which was the only region with a statistically significant decrease in BMD (23%, p < 0.001) at 24 months. Preoperative serum markers of bone turnover predicted the early temporary changes of periprosthetic BMD. The other patient-related factors failed to show any association with ...Continue Reading

References

Sep 1, 1993·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R EastellR G Russell
Apr 10, 1999·The Orthopedic Clinics of North America·F S HaddadC P Duncan
Mar 30, 2001·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·J M WilkinsonR Eastell
Jun 8, 2001·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·P K VenesmaaE M Alhava
Sep 30, 2003·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Katsuyuki YamaguchiTakeshi Fuji
Dec 9, 2003·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A I A RahmyI Fogelman
Dec 12, 2003·The Journal of Bone and Joint Surgery. American Volume·Julie GlowackiMeryl S LeBoff
Jan 2, 2004·Aging Clinical and Experimental Research·Jan DequekerFrank P Luyten
Feb 3, 2005·The Journal of Bone and Joint Surgery. American Volume·Mohit BhandariThomas A Einhorn
Nov 7, 2006·International Orthopaedics·Bart Cornelis Hendrikus van der WalAlphons Tonino
Oct 25, 2007·The Journal of Bone and Joint Surgery. British Volume·M NixonW Harper
Dec 1, 2007·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Allen E GoodshipMelanie J Coathup

❮ Previous
Next ❯

Citations

Mar 5, 2014·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Yi ShenWeili Wang
Dec 3, 2013·Current Osteoporosis Reports·R D RossA S Virdi
Apr 8, 2014·The Journal of Arthroplasty·Ashleen R KnustenSophia N Sangiorgio
Apr 18, 2012·Acta Orthopaedica. Supplementum·Tina Strømdal Wik
Mar 13, 2014·Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry·Elena GasbarraUmberto Tarantino
Sep 1, 2015·Revista española de cirugía ortopédica y traumatología·A Aguilar EzquerraJ Mateo Agudo
Mar 10, 2016·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Daigo MoritaTadashi Ito
Apr 21, 2011·Acta Orthopaedica·Berte BøeLars Nordsletten
Nov 30, 2010·Acta Orthopaedica·W S WatsonR M D Meek
Oct 21, 2011·The Journal of Bone and Joint Surgery. American Volume·Olof Gustaf SköldenbergPer Yngve Adolphson
Jun 7, 2018·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Ryan D RossDale R Sumner
Mar 26, 2016·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Shinya HayashiMasahiro Kurosaka
Jul 22, 2011·The Journal of Bone and Joint Surgery. American Volume·Alexander M KressLutz A Mueller
May 19, 2018·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Satoshi NagoyaToshihiko Yamashita
Jul 31, 2019·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Bernhard FlatøyLars Nordsletten
Aug 1, 2020·Current Osteoporosis Reports·Kyle D AndersonRyan D Ross
Feb 28, 2019·Journal of Orthopaedic Surgery and Research·Young-Kyun LeeKyung-Hoi Koo
Nov 2, 2019·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Theofilos S KarachaliosGeorge A Komnos

❮ Previous
Next ❯

Methods Mentioned

BETA
total hip arthroplasty
RSA

Software Mentioned

SPSS
SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.