Female urethral syndrome: clinical and urodynamic perspectives

Urology
G A Barbalias, E M Meares

Abstract

Eighteen women with the urethral syndrome were studied urodynamically with synchronous video-pressure flow studies and electromyography of the external urethral sphincter (EUS). When compared with an age and sex matched control group, the most striking finding was a significantly higher than normal maximum urethral closure pressure. Abnormal and low urinary flow rates, instability of the intraurethral pressure at rest, incomplete funnelling of the bladder neck, and distal urethral narrowing during voiding constitute other typical urodynamic findings in the female urethral syndrome. Detrusor-striated sphincter dyssynergia or primary striated sphincter spasm was not observed. Even though striated EUS spasticity cannot be excluded as a cause of this syndrome in some patients, an autonomically mediated spasm of the smooth muscle sphincter seems plausible to explain both our urodynamic findings and a favorable response of 4 patients treated with alpha-blocking agents.

References

Jan 1, 1975·British Journal of Urology·D L ReesJ E Wickham
Jun 1, 1981·British Journal of Urology·A J Splatt, D Weedon

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Citations

Feb 1, 1992·Journal of Behavioral Medicine·H C PhilipsD Samsom
Nov 2, 2005·International Urogynecology Journal and Pelvic Floor Dysfunction·Deepali Sinha, A Arunkalaivanan
Apr 30, 1999·European Journal of Obstetrics, Gynecology, and Reproductive Biology·H GürelM K Atilla
Oct 1, 1986·Genitourinary Medicine·R G FeldmanJ D Oriel
Jan 23, 2014·International Journal of Urology : Official Journal of the Japanese Urological Association·Harris PhillipVictor Chilaka
Sep 5, 2015·Der Urologe. Ausg. A·N M DregerD A Lazica
Aug 1, 1992·The Australian & New Zealand Journal of Obstetrics & Gynaecology·B Clarke

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