Feminized responses in fish to environmental estrogens

Toxicology Letters
J P Sumpter

Abstract

Effluent from sewage-treatment works entering British rivers contains an estrogenic chemical, or mixture of chemicals, that stimulates vitellogenin synthesis in male fish. If the effluent constitutes a significant proportion of the flow of the river, lengthy stretches of entire rivers can be estrogenic to fish. The chemical, or chemicals, responsible for this feminizing effect have not yet been identified. However, many man-made chemicals known to be estrogenic to fish (and other vertebrates) are present in effluent, although which of these, if any, is responsible for the effects noted when caged fish are placed in rivers is unclear presently. In laboratory studies, exposure to estrogenic alkylphenolic chemicals caused a reduction in the rate of testicular development in trout undergoing sexual maturation.

References

Nov 1, 1991·The Journal of Endocrinology·S J HyllnerC Haux
Oct 1, 1989·The Journal of Pharmacy and Pharmacology·G W Aherne, R Briggs
Jan 1, 1986·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·P A CopelandM Croft

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Citations

Jun 9, 2012·Analytical and Bioanalytical Chemistry·B HuertaD Barceló
Mar 7, 2008·Archives of Environmental Contamination and Toxicology·Ken M JeffriesKelly R Munkittrick
Aug 10, 2006·Environmental Monitoring and Assessment·R MaurícioF Santana
Mar 26, 2004·Ecotoxicology and Environmental Safety·S PawlowskiT Braunbeck
Jan 16, 2004·Water Research·Byoung-Cheun LeeYasumoto Magara
Jan 16, 2004·General and Comparative Endocrinology·Thea M EdwardsLouis J Guillette
Jun 7, 2005·General and Comparative Endocrinology·Stephen D McCormickBjörn Thrandur Björnsson
Aug 21, 2003·Ecotoxicology and Environmental Safety·K Van den BeltH Witters
Mar 26, 2004·Ecotoxicology and Environmental Safety·Jon M HemmingBarney Venables
Feb 11, 1999·Comparative Biochemistry and Physiology. Part C, Pharmacology, Toxicology & Endocrinology·D R Buhler, J L Wang-Buhler
Jul 12, 2002·Toxicology in Vitro : an International Journal Published in Association with BIBRA·S RadiceE Chiesara
Jun 6, 2000·Reproductive Toxicology·N P Moore
Dec 10, 2002·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Gary H ThorgaardYniv Palti
Feb 1, 2003·Environmental Toxicology and Pharmacology·Ron van der OostNico P E Vermeulen
Mar 10, 2001·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·F GagnéP D Hansen
Mar 10, 2001·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·J F TolarR A Angus
Jul 20, 2001·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·S ChatterjeeR Ghosh
Jun 6, 2002·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·Hai WangZijian Wang
Apr 1, 1997·Environmental Health Perspectives·A ArukweA Goksøyr
May 7, 1999·Environmental Health Perspectives·H R AndersenA M Soto
Mar 20, 2013·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Emily G Notch, Gregory D Mayer
Jul 17, 2010·The Science of the Total Environment·Caroline VanparysWim De Coen
Aug 6, 2009·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Seung Min OhKyu Hyuck Chung

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