Femoral lengthening in achondroplasia: magnitude of lengthening in relation to patterns of callus, stiffness of adjacent joints and fracture

The Journal of Bone and Joint Surgery. British Volume
K P VenkateshH-R Song

Abstract

Extensive limb lengthening may be indicated in achondroplastic patients who wish to achieve a height within the normal range for their population. However, increasing the magnitude of lengthening is associated with further complications particularly adjacent joint stiffness and fractures. We studied the relationship between the magnitude of femoral lengthening and callus pattern, adjacent joint stiffness and fracture of the regenerate bone in 40 femoral lengthenings in 20 achondroplastic patients. They were divided into two groups; group A had lengthening of less than 50% and group B of more than 50% of their initial femoral length. The patterns of radiological callus formation were classified according to shape, type and features. The incidence of callus features, knee stiffness and regenerate bone fracture were analysed in the two groups. Group B was associated with an increased incidence of concave, lateral and central callus shapes, adjacent joint and stiffness and fracture. Statistically, the incidence of stiffness in adjacent joints and regenerate bone fracture was significantly associated with the magnitude of lengthening. We suggest that careful radiological assessment of the patterns of callus formation is a useful met...Continue Reading

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Citations

Nov 14, 2015·Journal of Orthopaedics·Rolf D BurghardtJohn E Herzenberg
Apr 2, 2015·Journal of Orthopaedics·James DonaldsonChristopher Bradish
Aug 12, 2016·Indian Journal of Orthopaedics·Sanjay K ChilbuleVrisha Madhuri
Jun 8, 2018·Journal of Pediatric Orthopedics. Part B·Izumi KadonoNaoki Ishiguro
Feb 2, 2019·Calcified Tissue International·Masaki MatsushitaNaoki Ishiguro
Jun 4, 2019·Clinics in Orthopedic Surgery·Kyung Rae KoJoo Hwan Kim
Aug 18, 2020·American Journal of Medical Genetics. Part a·Pamela K ForemanSarah Landis
May 16, 2017·European Journal of Pediatrics·Daisuke HaradaYoshiki Seino
Jun 18, 2010·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Deborah Krakow, David L Rimoin
Jun 24, 2018·International Orthopaedics·Dmitry Y Borzunov, Alexander L Shastov
Jan 6, 2012·The Journal of Bone and Joint Surgery. British Volume·S-J KimH-R Song
Dec 1, 2018·BMC Musculoskeletal Disorders·Mi Hyun SongHae-Ryong Song
Feb 13, 2020·Archives of Orthopaedic and Trauma Surgery·Antonio Leiva-GeaFelipe Luna-González
Sep 19, 2020·Journal of Pediatric Orthopedics·Alexios D IliadisPeter Calder
Jul 18, 2015·Orthopedics·Anil BhaveJohn E Herzenberg

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