Femtoliter and attoliter electrochemical cells on chips

Analytical Chemistry
Tao LiLanqun Mao

Abstract

Chip electrochemistry is one of the top ambitions of today's electrochemistry. Here, a study for manufacturing electrochemical microcells on chips in a cost-effective, facile, and mass-producible way is presented. The ultrasmall, planar electrochemical cells, ranging from 140 femtoliter to 14 attoliter, can work independently as electroanalytical devices with embedded functional microelectrodes. Electrochemical responses of the miniaturized cells have been characterized by cyclic voltammetry. Ideal steady-state voltammograms were recorded with femtoliter volume cells, indicating the domination of a radical diffusion regime and a greatly improved signal/background ratio. Quasi-thin-layer behavior was observed for attoliter volume cells, which exhibited a special capability of offering accurately confined domains for redox processes. Positive feedback effect of the cells indicated that interactions between the close-by working and reference/counter microelectrodes can be well developed and potentially utilized for trace level electroanalysis. This study vividly offers i) a new protocol of electrochemical chip for applications, ii) a new tool for trace electroanalysis, and iii) a more approachable insight for single molecule elect...Continue Reading

References

Oct 31, 2002·Analytical Chemistry·Kevin P Troyer, R Mark Wightman
Apr 22, 2004·Lab on a Chip·Joël S RossierFrédéric Reymond
Nov 27, 2004·The Analyst·Damien W M Arrigan
Mar 15, 2005·Analytical Chemistry·Serge G LemayCees Dekker
May 24, 2005·The Analyst·Leif Nyholm
Aug 16, 2005·Analytical Chemistry·Gilles MarchandFrédéric Ginot
Sep 1, 2005·Analytical Chemistry·Xiaohong LiHeinz-Bernhard Kraatz
Feb 21, 2006·Physical Review Letters·Wenping HuKeiichi Torimitsu
Jun 8, 2006·Journal of the American Chemical Society·Gangli WangHenry S White
Jul 29, 2006·Lab on a Chip·Mairi E Sandison, Jonathan M Cooper
Sep 15, 2006·Analytical Chemistry·Peng Sun, Michael V Mirkin
Oct 13, 2006·Journal of the American Chemical Society·Gangli WangHenry S White
Dec 1, 2006·Annual Review of Physical Chemistry·Fang ChenN J Tao
Feb 15, 2007·Analytical Chemistry·Cynthia G ZoskiMilena Koudelka-Hep
Mar 21, 2007·Analytical Chemistry·Yvonne H LanyonDamien W M Arrigan
Feb 10, 1995·Science·F R Fan, A J Bard
Jun 11, 2008·Journal of the American Chemical Society·Peng Sun, Michael V Mirkin
Sep 8, 2009·Nature Nanotechnology·Kasper Moth-Poulsen, Thomas Bjørnholm
Mar 11, 2010·Advanced Materials·Tao LiDaoben Zhu
Oct 1, 1999·Analytical Chemistry·J S RossierH H Girault

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Citations

Mar 22, 2016·Analytical Chemistry·Christopher J FreemanMaryanne M Collinson
Aug 6, 2010·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Qian WangAllen J Bard
Oct 23, 2010·Nanoscale·Tao Li, Wenping Hu
Apr 23, 2011·Analytical Chemistry·Liza RassaeiSerge G Lemay
Oct 5, 2013·Analytical Chemistry·Binod RizalMichael J Naughton
Apr 20, 2011·Analytical Chemistry·Jerome WorkmanMel Koch

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