PMID: 641947Apr 1, 1978Paper

Fertility in 47,XXX and 45,X patients

Journal of Medical Genetics
J Dewhurst


Female patients with a sex chromosome abnormality may be fertile. In patients with a 47,XXX cell line there appears to be an increased risk of a cytogenetically abnormal child but the extent of this risk cannot yet be determined; it is probably lower in the non-mosaic 47,XXX patient than the mosaic 46,XX/47,XXX one. Patients with a 45,X cell line rarly become pregnant, and when they do they appear to have a high risk of an abnormal child or repeated unsuccessfuly pregnancies; this risk is certainly exaggerated by the method of reporting; when the poor reproductive perforamcne is first identified leading to the recognition of the maternal cytogenetic fault, the reproductive failure rate is naturally high; when the maternal fault is first identified and the reproductive history then established far better results are evident.


Jan 1, 1976·Acta Obstetricia Et Gynecologica Scandinavica·J Philip, V Sele
Jan 1, 1975·Humangenetik·J ZizkaJ Nielsen
Mar 1, 1975·Journal of Medical Genetics·M T TsuangL E De Bault
Oct 23, 1975·The New England Journal of Medicine·H J KimK Hirschhorn
Mar 25, 1976·The New England Journal of Medicine·P S Gerald
Apr 29, 1972·Lancet·M GeislerK H Degenhardt
Jan 27, 1973·Lancet·E Lieber, J Berger
Mar 25, 1972·Lancet·A G BaikieJ N Lickiss
May 3, 1969·Lancet·M H Hughes, P J Speller
Jul 26, 1969·Lancet·V PredescuE Constantinescu
Jan 15, 1973·American Journal of Obstetrics and Gynecology·H J GraceW E Edge
Dec 1, 1967·Acta Paediatrica Japonica; Overseas Edition·M Mino, T Takai
Jan 1, 1972·The Journal of Pediatrics·P A Baird, B P De Jong
Dec 1, 1971·The Journal of Obstetrics and Gynaecology of the British Commonwealth·M LucasS Blunt
Nov 1, 1971·The Australian & New Zealand Journal of Obstetrics & Gynaecology·E V MackayK G Cockburn
Aug 15, 1970·American Journal of Obstetrics and Gynecology·D T Arakaki, S H Waxman
Sep 1, 1971·The Journal of Pediatrics·W J StraderG D Lundberg
Sep 1, 1968·Fertility and Sterility·H W Kava, H P Klinger
Sep 1, 1968·Journal of Medical Genetics·N MacleanJ A Strong
Jul 1, 1966·The Anatomical Record·R P Singh, D H Carr
Aug 10, 1963·Lancet·A JADRESICM LAZO
Jul 1, 1963·The Journal of Pediatrics·D K BRIGGSJ VINOGRAD
Oct 22, 1963·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·T G BAKER
May 1, 1965·Lancet·W ROSENKRANZ

❮ Previous
Next ❯


Jan 1, 1988·Archives of Gynecology and Obstetrics·D GlaserI H Pawlowitzki
Dec 1, 1992·European Journal of Pediatrics·G MassaJ P Fryns
Jul 1, 1986·Indian Journal of Pediatrics·A T Tharapel, R S Wilroy
Apr 1, 1987·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·W M HagueH S Jacobs
Feb 1, 1989·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Y JacquemynP Buytaert
Mar 1, 1982·Cancer Genetics and Cytogenetics·R S ChagantiB D Clarkson
Sep 2, 1978·Lancet·M P Rowley, G W Dahlenburg
Dec 1, 1982·Journal of Medical Genetics·C R King, R N Schimke
Mar 1, 1991·Journal of Medical Genetics·A CockwellP Jacobs
May 13, 2010·Orphanet Journal of Rare Diseases·Nicole R TartagliaLennie Wilson
Aug 1, 2013·Indian Journal of Human Genetics·Faeza Abdel Mogib El-Dahtory
Aug 1, 1993·Journal of Assisted Reproduction and Genetics·P De SutterM Coppens
Nov 1, 1979·British Journal of Obstetrics and Gynaecology·J NielsenK B Hansen
Jul 1, 1986·Pediatric Annals·D K Edmonds, J Dewhurst
Sep 1, 1985·British Journal of Obstetrics and Gynaecology·A T TharapelR M Bannerman
May 1, 1989·British Journal of Obstetrics and Gynaecology·W M HagueH S Jacobs
May 2, 2006·Current Opinion in Genetics & Development·Heather HallTerry Hassold
Apr 1, 1989·The Journal of Pediatrics·A A MassaranoC G Brook
Jul 3, 2003·Obstetrics and Gynecology Clinics of North America·Megan Freebury Karnis, Richard H Reindollar
Sep 5, 2002·American Journal of Medical Genetics·David SchlessingerAntonino Forabosco
May 1, 1989·Pharmacology & Toxicology·K D JørgensenH Orskov
Jan 1, 1980·American Journal of Medical Genetics·T ToussiA Bergeron
Jan 1, 1980·American Journal of Medical Genetics·G KohnM M Cohen
Feb 15, 2002·Endocrine Reviews·M ElsheikhJ A H Wass
Apr 1, 1984·Clinical Genetics·P H FitzgeraldP McCormick
Apr 1, 1992·Clinical Genetics·M R Verschraegen-SpaeA De Paepe
Dec 1, 1984·Clinical Genetics·M C AyusoG Mendoza
May 1, 1983·Clinical Genetics·J P FrynsH van den Berghe

❮ Previous
Next ❯

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.


Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.


Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.