Fertility of Danish battery workers exposed to lead

International Journal of Epidemiology
J P Bonde, H Kolstad

Abstract

Inorganic lead may impair male fecundity through its action on the germinal epithelium, the endocrine system or both, but information on possible impact on fertility in exposed populations is limited. Fertility was examined in 1349 male battery plant employees and in 9596 reference company employees over a follow-up of 25,949 and 183,414 person years respectively. The cohorts were identified by records in a national pension fund and information on births was obtained from the Danish Population Register. In a subset of the battery worker cohort, the average level of lead in blood was 35.9 micrograms/dl (4639 blood samples on 1654 person years in 400 workers; SD 13.0; range 3-125). The birth rate was analysed by logistic regression on occupational exposure and several extraneous determinants (age, parity, calendar year, and previous children). The birth-rate was not reduced in years at risk from exposure to lead in comparison with years not-at-risk; either in comparison with not-at-risk years within the battery plant cohort (odds ratio [OR] = 0.997, 95% confidence interval [CI]: 0.88-1.13), or in comparison with the external reference population (OR = 0.983, 95% CI: 0.87-1.11). Inorganic lead seems not to impair fertility among D...Continue Reading

Citations

Oct 13, 2004·Occupational and Environmental Medicine·C-Y ShiauP-C Chen
Sep 25, 2003·Occupational and Environmental Medicine·M JoffeUNKNOWN Asclepios
Dec 21, 2007·Reproductive Toxicology·Marcia C InhornAntoine B Hannoun
Feb 17, 2006·Reproductive Toxicology·Carsten Rajendran SimonsenJens Peter Bonde
Dec 28, 1999·Journal of Occupational and Environmental Medicine·A IrgensM Ulstein
Dec 17, 2004·Human Reproduction Update·Edward V YounglaiWarren G Foster
May 10, 2005·Birth Defects Research. Part A, Clinical and Molecular Teratology·David C Bellinger
Dec 7, 2019·Demography·Daniel S Grossman, David J G Slusky
Oct 6, 2000·Epidemiology·M SallménM Nurminen
May 12, 2019·Environmental Science and Pollution Research International·Chin-En AiLing-Chu Chien
Feb 6, 2019·International Journal of Environmental Research and Public Health·Saverio CainiDomenico Palli
Mar 7, 2006·Human Reproduction·John F JarrellMauricio Hernández-Avila
Feb 13, 1999·American Journal of Industrial Medicine·S ViskumP Grandjean
Aug 12, 2016·Turkish Journal of Medical Sciences·Basima Al-JubooriAnam Al-Salihi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.