Fertility preservation and breast cancer: a review

Ecancermedicalscience
María de PedroBelén Martín

Abstract

Breast cancer is the most common malignancy in women, and its incidence increases with age, with the majority of patients diagnosed after menopause. However, in 15-25% of cases, patients are premenopausal at the time of diagnosis, and about 7% of them are below the age of 40. Therefore, a considerable amount of young women are diagnosed with breast cancer during their reproductive life. Within this group, most cancer cases require cytotoxic chemotherapy and/or hormone therapy, which are responsible for a decrease in the patients' reproductive function, along with their age. The efficacy of such treatments, among other factors, has led to a high five-year-survival rate, which results in an increasing number of young women who survive breast cancer before having fulfilled their reproductive wishes, especially considering the current trend to delay pregnancy until the late 30s or early 40s in developed countries. The combination of these factors justifies the importance of fertility preservation and reproductive counselling at the time of breast cancer diagnosis in young women. A wide range of fertility preservation techniques has been developed, such as ovarian suppression, oocyte and embryo cryopreservation, immature oocyte retr...Continue Reading

Citations

Dec 5, 2015·Expert Review of Anticancer Therapy·Filippo MontemurroFabio Puglisi
Apr 26, 2017·European Journal of Cancer Care·P-L HsiehC-J Tai
May 27, 2017·Human Fertility : Journal of the British Fertility Society·Yazan AbdallahCheryl Fitzgerald
Apr 14, 2020·Journal of Adolescent and Young Adult Oncology·Mohd Faizal AhmadNao Suzuki
Sep 14, 2016·JAAPA : Official Journal of the American Academy of Physician Assistants·Kathryn Trotter, April Stouder
Oct 22, 2020·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Yujie WangKrisztina D László
Oct 25, 2020·International Journal of Molecular Sciences·Hyun-Woong ChoTak Kim
Jul 25, 2021·International Journal of Molecular Sciences·Seongmin KimTak Kim
Aug 31, 2021·Critical Reviews in Oncology/hematology·Santiago MoragónMaría Teresa Martínez

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Methods Mentioned

BETA
contraception

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