Fertility-sparing for young patients with gynecologic cancer: How MRI can guide patient selection prior to conservative management

Abdominal Radiology
Sinead H McEvoyYulia Lakhman

Abstract

Historically, cancer treatment has emphasized measures for the "cure" regardless of the long-term consequences. Advances in cancer detection and treatment have resulted in improved outcomes bringing to the fore various quality of life considerations including future fertility. For many young cancer patients, fertility preservation is now an integral component of clinical decision-making and treatment design. Optimal fertility-sparing options for young patients with gynecologic cancer are influenced by patient age, primary cancer, treatment regimens, and patient preferences. Possible approaches include embryo or oocyte cryopreservation, ovarian transposition, conservative surgery, and conservative medical treatment to delay radical surgery. These may be used alone or in combination to maximize fertility preservation. Awareness of the various fertility-sparing options, eligibility criteria, and the central role of magnetic resonance imaging in the proper selection of patients will enable radiologists to produce complete clinically relevant imaging reports and serve as effective consultants to referring clinicians. Knowledge of the potential imaging pitfalls is essential to avoid misinterpretation and guide appropriate management.

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Citations

Feb 14, 2019·Insights Into Imaging·María Milagros Otero-GarcíaMagda Szewczyk-Bieda
Mar 25, 2019·Abdominal Radiology·Patricia BalcacerBabak Litkouhi
Nov 4, 2020·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Francesca MoroAntonia Carla Testa
Mar 13, 2021·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Blanca Segarra-VidalHenrik Falconer
May 1, 2021·The British Journal of Radiology·Elizabeth A SadowskiIsabelle Thomassin-Naggara
May 15, 2021·The British Journal of Radiology·Aki Kido, Yuji Nakamoto

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