Fetal arterial Doppler-IUGR and hypoxia

European Journal of Obstetrics, Gynecology, and Reproductive Biology
P Arbeille

Abstract

Vascular resistances of various fetal areas are assessed by Doppler ultrasound. The PI, RI and S/D indices are measured on the cerebral, renal, aortic and umbilical Doppler spectrum. Ratios of these indices based on the comparison of the cerebral (Rc) and the umbilical (Rp) resistances, or carotid (Rcc) and umbilical resistances, or cerebral (Rc) and aortic (Rao) resistances (Rc/Rp or Rp/Rcc, or Rc/Rao), measure the flow redistribution between the placenta and brain. The umbilical resistance indices, when greater than the upper limit of the normal range (> 2sd) are frequently associated with IUGR. (Sensitivity about 65 to 70%). Absent end diastolic flow is most of the time associated with severe IUGR and hypoxia and poor fetal outcome. A fairly good correlation was found between the existence of significantly decreased (< .2.sd) cerebral resistance and the development of post asphyxial encephalopathy in the neonate (Specificity 75% Sensitivity 87%). The earliest detectors of IUGR and hypoxia are the cerebral-umbilical cerebral-carotid, or cerebral-aortic ratios (Sensitivity 85% specificity 90%). When used as predictor of poor perinatal outcome in growth retarded fetuses, the cerebral umbilical ratio shows a sensitivity of 90% c...Continue Reading

References

Mar 1, 1992·Obstetrics and Gynecology·D GramelliniA Merialdi
Jul 1, 1989·American Journal of Obstetrics and Gynecology·S VyasS Campbell
Dec 1, 1989·American Journal of Obstetrics and Gynecology·M Y DivonO Langer
Oct 22, 1988·BMJ : British Medical Journal·K H NicolaidesS Campbell
Jan 1, 1987·Acta Obstetricia Et Gynecologica Scandinavica·J Laurin, P H Persson
Aug 1, 1994·European Journal of Obstetrics, Gynecology, and Reproductive Biology·P ArbeilleM Deufel
May 1, 1996·European Journal of Obstetrics, Gynecology, and Reproductive Biology·A FignonP Arbeille
Jan 1, 1992·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·P BonninJ P Martineaud

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Citations

Nov 14, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S SkrablinT Goluza
Oct 18, 2001·European Journal of Obstetrics, Gynecology, and Reproductive Biology· Deren OR O Bahado-Singh
Mar 8, 2002·Archives of Disease in Childhood. Fetal and Neonatal Edition·A M SchreuderP L Hope
Jun 17, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Brian J Koos
Jul 4, 2006·Journal of the Society for Gynecologic Investigation·Paul SettleStephen W D'Souza
Nov 4, 2017·The Journal of Physiology·Anderson H KuoPeter W Nathanielsz
Jan 29, 2018·Journal of Developmental Origins of Health and Disease·A BarberoF Berlinguer
Aug 18, 2006·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Mark WareingGregor K Fyfe
Sep 9, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Mickael CoupéYinghui H Li
Jan 1, 2005·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Monica LongoGeorge R Saade
May 1, 2018·Frontiers in Physiology·Graham J Burton, Eric Jauniaux

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