PMID: 11489591Aug 8, 2001Paper

Fetal effects of cocaine: an updated meta-analysis

Reproductive Toxicology
A AddisG Koren

Abstract

A very large number of women in the reproductive age group consume cocaine, leading to grave concerns regarding the long term health of millions of children after in utero exposure. The results of controlled studies have been contradictory, leading to confusion, and, possible, misinformation and misperception of teratogenic risk. To systematically review available data on pregnancy outcome when the mother consumed cocaine. A meta-analysis of all epidemiologic studies based on a priori criteria was conducted. Comparisons of adverse events in subgroups of exposed vs. unexposed children were performed. Analyses were based on several exposure groups: mainly cocaine, cocaine plus polydrug, polydrug but no cocaine, and drug free. Thirty three studies met our inclusion criteria. For all end points of interest (rates of major malformations, low birth weight, prematurity, placental abruption, premature rupture of membrane [PROM], and mean birth weight, length and head circumference), cocaine-exposed infants had higher risks than children of women not exposed to any drug. However, most of these adverse effects were nullified when cocaine exposed children were compared to children exposed to polydrug but no cocaine. Only the risk of place...Continue Reading

References

Dec 1, 1992·Teratology·G KorenI Robieux
Sep 1, 1992·Journal of Analytical Toxicology·M G RippleS Schwartz
Jan 1, 1992·Journal of Substance Abuse Treatment·I E SmithA Falek
Oct 1, 1992·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·S S LiuR Glassenberg
May 1, 1992·Pediatric Pathology·J KleinG Koren
Oct 15, 1992·The American Journal of Cardiology·M A Mendelson, J Chandler
Sep 3, 1992·The New England Journal of Medicine·M Bériault
Nov 1, 1992·Epilepsia·A J PetersR L Gilmore
Dec 11, 1992·Biochemical Medicine and Metabolic Biology·J T HernandezA J Prange
Mar 13, 1992·Journal of Chromatography·S P BrowneG T Yee
Sep 1, 1992·Teratology·M L Martin, M J Khoury
Jan 1, 1992·The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association·E F HarrisE A Tolley
Apr 1, 1992·Archives of Physical Medicine and Rehabilitation·K A Sheinbaum, A Badell
Mar 1, 1992·Ophthalmology·W V GoodJ A Kobori
May 1, 1992·American Journal of Public Health·J G FeldmanM Salwen
May 1, 1992·Southern Medical Journal·S Sarpong, V Headings
Jun 1, 1992·AJR. American Journal of Roentgenology·T R HallM I Boechat
Jun 1, 1992·The American Journal of Psychiatry·M GalanterH Franco
Mar 1, 1992·Neurotoxicology and Teratology·J W Schneider, I J Chasnoff
Jul 1, 1992·American Journal of Public Health·J SackoffA Grunebaum
Apr 1, 1992·The Journal of Pediatrics·D R Neuspiel, S C Hamel
Aug 6, 1992·The New England Journal of Medicine·J J Volpe
Aug 1, 1992·The Journal of Pediatrics·P T Horn
Jul 1, 1991·MCN. the American Journal of Maternal Child Nursing·P Lone
May 1, 1991·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·H R CohenW R Crombleholme
Nov 23, 1991·Lancet·J N van den AnkerP J Sauer
Dec 1, 1991·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·L S CohenI J Chasnoff
Mar 1, 1991·Anesthesiology·Z Herschman, C Aaron
Jan 1, 1992·MCN. the American Journal of Maternal Child Nursing·M W Byrne, H M Lerner
Sep 15, 1991·American Journal of Medical Genetics·M J KhouryM C Lynberg
Nov 1, 1991·Journal of Pediatric Health Care : Official Publication of National Association of Pediatric Nurse Associates & Practitioners·E L Abel
Sep 1, 1991·Neurotoxicology and Teratology·S W JacobsonM G Kaplan
Nov 1, 1991·Journal of Medical Genetics·M LessickJ Israel
Jan 11, 1991·Reproductive Toxicology·M A Plessinger, J R Woods
Jul 1, 1991·Nursing Research·M E Fogarty
Jul 1, 1991·Neurotoxicology and Teratology·G A Richardson, N L Day
Jan 1, 1991·International Journal of Rehabilitation Research. Internationale Zeitschrift Für Rehabilitationsforschung. Revue Internationale De Recherches De Réadaptation·I J Deoliveira, B J Cratty
Jul 1, 1991·Teratology·R P KapurT H Shepard

❮ Previous
Next ❯

Citations

Dec 18, 2001·Prenatal Diagnosis
Oct 25, 2002·Teratology·Karen S Kuehl, Christopher Loffredo
Mar 17, 2004·Neuroscience and Biobehavioral Reviews·John A Harvey
Jan 11, 2011·Journal of Addictive Diseases·Mishka Terplan, Tricia Wright
Aug 25, 2012·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Sarah C M RobertsDiana Greene Foster
Oct 11, 2007·Obstetrical & Gynecological Survey·Ashley H Schempf
Jan 15, 2013·Clinical Obstetrics and Gynecology·Eleazar Soto, Ray Bahado-Singh
Feb 25, 2003·Archives of Disease in Childhood. Fetal and Neonatal Edition·B Bar-OzG Koren
Sep 15, 2005·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Merry LittleJoel G Ray
Dec 23, 2008·Pediatric Radiology·Marian van HuisRick R Van Rijn
Oct 22, 2004·Journal of Perinatology : Official Journal of the California Perinatal Association·Ellen L WolfeKevin L Delucchi
Jul 4, 2008·Journal of Perinatology : Official Journal of the California Perinatal Association·D P MontgomeryR D Christensen
Feb 19, 2016·Journal of Public Health·Christopher D JohnsonShantini Paranjothy
Apr 23, 2010·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Lisa LefebvreLydia Pantea
Oct 25, 2012·La Presse médicale·Pascal Courty, Laure Nacache
Jan 28, 2004·Birth Defects Research. Part A, Clinical and Molecular Teratology·Maki KashiwagiGundula Hebisch
Apr 25, 2012·Reproductive Toxicology·S OrtigosaO Garcia-Algar
Feb 15, 2011·International Journal of Obstetric Anesthesia·K W ArendtL C Tsen
Oct 12, 2010·Life Sciences·Vadivel Ganapathy
Oct 20, 2009·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·C LejeuneP Gressens
Nov 26, 2008·Fertility and Sterility·UNKNOWN Practice Committee of American Society for Reproductive Medicine in collaboration with Society for Reproductive Endocrinolog
May 21, 2005·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Robyn KennareAnnabelle Chan
Sep 3, 2011·Perspectives on Sexual and Reproductive Health·Marleen M H J van GelderNel Roeleveld
Jan 16, 2010·BJOG : an International Journal of Obstetrics and Gynaecology·J W GarganoR Fisher
Aug 6, 2004·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Javier Valero De BernabéVicente Domínguez-Rojas
Sep 21, 2015·Current Psychiatry Reports·Ariadna Forray, Dawn Foster
Jan 18, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Joey GareriGideon Koren
Nov 3, 2004·Clinics in Perinatology·Michael J PaidasYale S Arkel
May 26, 2004·Pediatric Clinics of North America·Enrique M OstreaMaria Asuncion Silvestre
Jan 25, 2011·American Journal of Obstetrics and Gynecology·Katy GouinUNKNOWN Knowledge Synthesis group on Determinants of Low Birth Weight and Preterm Births
Dec 17, 2008·American Journal of Obstetrics and Gynecology·R Louise FloydRobert J Sokol
Nov 6, 2007·American Journal of Obstetrics and Gynecology·Adam J DuhlUNKNOWN Pregnancy and Thrombosis Working Group
May 30, 2006·Developmental Biology·Stacey Sedore WillardClaire Cronmiller
Nov 25, 2016·Journal of Analytical Toxicology·Fang WuGwendolyn A McMillin
Aug 24, 2005·Seminars in Perinatology·Michael J PaidasYale S Arkel
Aug 1, 2013·Reproductive Sciences·Marianna Pina RambaldiMichael J Paidas
Oct 14, 2005·The Journal of the Royal Society for the Promotion of Health·Anne Greenough, Zainab Kassim
Jan 18, 2018·Fundamental & Clinical Pharmacology·Liselotte PochardUNKNOWN French Addictovigilance Network
Apr 16, 2010·The Cochrane Database of Systematic Reviews·Kirsty AndersonPhilippa Middleton
Aug 23, 2018·AIDS·Micah PiskeUNKNOWN CIHR Team Grant on Cellular Aging and HIV Comorbidities in Women and Children (CARMA)

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Obstetrics, Gynecology, and Reproductive Biology
O Fajemirokun-Odudeyi, S W Lindow
The Australian & New Zealand Journal of Obstetrics & Gynaecology
L R LeaderB Stenning
© 2021 Meta ULC. All rights reserved