PMID: 10826584May 29, 2000Paper

Fetal haemodynamic changes in fetuses during fetal development evaluated by arterial pressure pulse and blood flow velocity waveforms

BJOG : an International Journal of Obstetrics and Gynaecology
A MoriT Makino


To study the relation between diameter pulse (pressure pulse) and flow velocity waveforms in the fetal descending aorta in fetuses with intrauterine growth retardation and acceleration. Blood flow through a tubular system can be expressed by the ratio of blood pressure to vascular resistance. Doppler ultrasound and a phase locked loop echo tracking system coupled to a B-mode ultrasonic imager (central frequency 3.5 MHz) were used to assess downstream resistance and change in blood pressure, respectively. Tertiary referral unit in a teaching hospital Serial study between 21 and 40 weeks of 22 women with normally grown fetuses at intervals of four weeks; 25 women with small for gestational age fetuses with uteroplacental insufficiency (high umbilical artery pulsatility index); and six women with large for gestational age fetuses. We measured the maximum systolic and minimum diastolic diameter of the fetal descending aorta (the pulse amplitude) and then calculated the pulsatile waveform time integral above the least diastolic diameter (pulsatile area) and total waveform time integral (perfusion area). Normal fetal growth was associated with an increase in systolic and diastolic diameters in the fetal descending aorta with advancin...Continue Reading


Jan 1, 1978·Bulletin of Mathematical Biology·C N WeygandtM L Cole
May 1, 1991·Statistics in Medicine·P Royston
Jan 1, 1989·Ultrasound in Medicine & Biology·D GustafssonG Gennser
May 1, 1987·American Journal of Obstetrics and Gynecology·G R DeVoreL D Platt
May 25, 1987·Ugeskrift for laeger·K Sørensen
Jan 1, 1985·British Journal of Obstetrics and Gynaecology·B J TrudingerL Collins
May 30, 1993·Statistics in Medicine·D G Altman
Dec 31, 1997·British Journal of Obstetrics and Gynaecology·A MoriY Takeda

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